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• W2029672283 abstract "Transport of molecules across membrane channels is investigated theoretically using exactly solvable discrete stochastic site-binding models. It is shown that the interaction potential between molecules and the channel has a strong effect on translocation dynamics. The presence of attractive binding sites in the pore accelerates the particle current for small concentrations outside of the membrane, while for large concentrations, surprisingly, repulsive binding sites produce the most optimal transport. In addition, asymmetry of the interaction potential also strongly influences the channel transport. The mechanism of these phenomena are discussed using the details of particle dynamics at the binding sites." @default.
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• W2029672283 date "2007-01-26" @default.
• W2029672283 modified "2023-10-17" @default.
• W2029672283 title "Channel-Facilitated Molecular Transport across Membranes: Attraction, Repulsion, and Asymmetry" @default.
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• W2029672283 doi "https://doi.org/10.1103/physrevlett.98.048105" @default.
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