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• W2029680019 abstract "ObjectiveCounseling prior to cancer treatment reduces reproductive concerns and improves long-term quality of life. We sought to identify the population at highest risk for post-treatment reproductive concerns in order to effectively target post-treatment counseling.DesignCross-sectional survey.Materials and MethodsWe contacted 2532 women from the California Cancer Registry (randomly sampled; diagnosed from 1993-2007; ages 18-40 at diagnosis) with non-gynecological cancers to complete a survey containing a Reproductive Concerns Scale. Using t-tests and linear/logistic regression, we assessed the association between reproductive concerns scores (RCS) and the following variables: WHO Quality of Life (QoL), parenting desires, parity, history of adoption, treatment type, age, ethnic/gender identity, and quality of counseling.Results1041 women responded to the survey and 475 completed the RCS. Overall, in-depth pre-treatment counseling was associated with lower RCS (P<0.01). However, after controlling for the effect of pre-treatment counseling, a sub-population of patients remains at risk for higher RCS: those desiring future children at diagnosis (14 vs. 4.9, P<0.01); those who are nulliparous (8.6 vs. 4.1, P<0.01); and those treated with chemotherapy and radiation (vs. chemo alone) (13 vs. 4.1, P<0.01). Beyond having at least one child at diagnosis, incremental increase in family size does not reduce RCS. Similarly, there was no significant change in RCS associated with history of adoption prior to treatment, age at treatment, ethnicity, or gender identity. RCS was also associated with significantly decreased QoL (P<0.01).ConclusionAlthough in-depth pre-treatment counseling is beneficial, women who are nulliparous, have been exposed to chemoradiation, and desire future children remain at risk for significant reproductive concerns which are associated with a lower quality of life. As a result, this high-risk population may benefit from additional counseling post-treatment. ObjectiveCounseling prior to cancer treatment reduces reproductive concerns and improves long-term quality of life. We sought to identify the population at highest risk for post-treatment reproductive concerns in order to effectively target post-treatment counseling. Counseling prior to cancer treatment reduces reproductive concerns and improves long-term quality of life. We sought to identify the population at highest risk for post-treatment reproductive concerns in order to effectively target post-treatment counseling. DesignCross-sectional survey. Cross-sectional survey. Materials and MethodsWe contacted 2532 women from the California Cancer Registry (randomly sampled; diagnosed from 1993-2007; ages 18-40 at diagnosis) with non-gynecological cancers to complete a survey containing a Reproductive Concerns Scale. Using t-tests and linear/logistic regression, we assessed the association between reproductive concerns scores (RCS) and the following variables: WHO Quality of Life (QoL), parenting desires, parity, history of adoption, treatment type, age, ethnic/gender identity, and quality of counseling. We contacted 2532 women from the California Cancer Registry (randomly sampled; diagnosed from 1993-2007; ages 18-40 at diagnosis) with non-gynecological cancers to complete a survey containing a Reproductive Concerns Scale. Using t-tests and linear/logistic regression, we assessed the association between reproductive concerns scores (RCS) and the following variables: WHO Quality of Life (QoL), parenting desires, parity, history of adoption, treatment type, age, ethnic/gender identity, and quality of counseling. Results1041 women responded to the survey and 475 completed the RCS. Overall, in-depth pre-treatment counseling was associated with lower RCS (P<0.01). However, after controlling for the effect of pre-treatment counseling, a sub-population of patients remains at risk for higher RCS: those desiring future children at diagnosis (14 vs. 4.9, P<0.01); those who are nulliparous (8.6 vs. 4.1, P<0.01); and those treated with chemotherapy and radiation (vs. chemo alone) (13 vs. 4.1, P<0.01). Beyond having at least one child at diagnosis, incremental increase in family size does not reduce RCS. Similarly, there was no significant change in RCS associated with history of adoption prior to treatment, age at treatment, ethnicity, or gender identity. RCS was also associated with significantly decreased QoL (P<0.01). 1041 women responded to the survey and 475 completed the RCS. Overall, in-depth pre-treatment counseling was associated with lower RCS (P<0.01). However, after controlling for the effect of pre-treatment counseling, a sub-population of patients remains at risk for higher RCS: those desiring future children at diagnosis (14 vs. 4.9, P<0.01); those who are nulliparous (8.6 vs. 4.1, P<0.01); and those treated with chemotherapy and radiation (vs. chemo alone) (13 vs. 4.1, P<0.01). Beyond having at least one child at diagnosis, incremental increase in family size does not reduce RCS. Similarly, there was no significant change in RCS associated with history of adoption prior to treatment, age at treatment, ethnicity, or gender identity. RCS was also associated with significantly decreased QoL (P<0.01). ConclusionAlthough in-depth pre-treatment counseling is beneficial, women who are nulliparous, have been exposed to chemoradiation, and desire future children remain at risk for significant reproductive concerns which are associated with a lower quality of life. As a result, this high-risk population may benefit from additional counseling post-treatment. Although in-depth pre-treatment counseling is beneficial, women who are nulliparous, have been exposed to chemoradiation, and desire future children remain at risk for significant reproductive concerns which are associated with a lower quality of life. As a result, this high-risk population may benefit from additional counseling post-treatment." @default.
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• W2029680019 date "2012-09-01" @default.
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• W2029680019 title "Predictors of reproductive concerns for survivors of reproductive age cancers: targeting post-treatment counseling for high-risk populations" @default.
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