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• W2029693415 abstract "A histologic review was undertaken of 35 lymphoreticular disorders that developed in primary immunodeficiency patients from the Immunodeficiency Cancer Registry. Twenty-one (60%) of the lesions were non-Hodgkin's lymphomas: these included eight B-immunoblastic sarcomas. Eight (23%) of the lesions were Hodgkin's disease, with a high frequency of lymphocytic depletion type in an unusually young age group. Three lesions (8.5%) represented abnormal proliferative processes, which could not be definitely categorized as either benign or malignant. There were only two acute lymphoblastic leukemias (6%). Differences were found between lymphomas arising in Wiskott-Aldrich syndrome and those occurring in ataxia-telangiectasia; this suggests that different pathogenetic mechanisms might operate in their development. The lymphomas in Wiskott-Aldrich syndrome were all of non-Hodgkin's type, predominantly B-immunoblastic sarcomas, and presented as localized extranodal infiltrates. The lymphomas in ataxia-telangiectasia were either Hodgkin's disease, mostly of lymphocytic depletion type, or non-Hodgkin's lymphomas of the histologic subtypes associated with 14q translocations." @default.
• W2029693415 created "2016-06-24" @default.
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• W2029693415 date "1980-08-15" @default.
• W2029693415 modified "2023-09-24" @default.
• W2029693415 title "Lymphoreticular disorders in primary immunodeficiencies: New findings based on an up-to-date histologic classification of 35 cases" @default.
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• W2029693415 doi "https://doi.org/10.1002/1097-0142(19800815)46:4<692::aid-cncr2820460410>3.0.co;2-q" @default.
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