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- W2029702783 abstract "This investigation attempted to assess the hemodynamic effects of short-term use of a typical combined contraceptive pill in both recumbent and upright positions. In addition an attempt was made to evaluate the part played by each component of the pill in the changes observed. Subjects were 49 healthy women ages 20 to 34 who had not previously used contraceptive pills. 29 women were given Lyndiol 2.5 2.5 mg of lynestrenol and .075 mg of mestranol for 2 months; 10 received lynestrenol only for 10 to 13 days. In 21 women a radiocardiographic examination was performed in the recumbent and upright positions. Blood pressure was measured in recumbency. Also in 9 subjects blood pressure was measured after they had been standing for 15 minutes. Significant increases in cardiac output blood volume and stroke volume were observed after the combined oral contraceptive therapy. No significant changes in blood pressure as compared with pretreatment results were found. Heart rate decreased slightly. Periph eral resistance decreased slightly. Body weigth increased significantly with the combined therapy but not with mestranol. Similar changes were recorded in the women given mestranol alone but none of the changes in those given lynestrol alone. The cardiovascular response was not significantly altered by the upright position. Results indicate that the hemodynamic changes observed during combined estrogen/progestogen th erapy are caused by the estrogen." @default.
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- W2029702783 title "Haemodynamic effects of combined oestrogen-progestogen oral contraceptives." @default.
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