FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2029721543> ?p ?o ?g. }

• W2029721543 endingPage "3447" @default.
• W2029721543 startingPage "3441" @default.
• W2029721543 abstract "Chronic wounds continue to be a global healthcare concern. Thus, the development of new nanoparticle-based therapies that treat multiple symptoms of these “non-healing” wounds without encouraging antibiotic resistance is imperative. One potential solution is to use chitosan, a naturally antimicrobial polycation, which can spontaneously form polyelectrolyte complexes when mixed with a polyanion in appropriate aqueous conditions. The requirement of at least two different polymers opens up the opportunity for us to form chitosan complexes with an additional functional polyanion. In this study, chitosan:pectin (CS:Pec) nanoparticles were synthesized using an aqueous spontaneous ionic gelation method. Systematically, a number of parameters, polymer concentration, addition order, mass ratio, and solution pH, were explored and their effect on nanoparticle formation was determined. The size and surface charge of the particles were characterized, as well as their morphology using transmission electron microscopy. The effect of polymer concentration and addition order on the nanoparticles was found to be similar to that of other chitosan:polyanion complexes. The mass ratio was tuned to create nanoparticles with a chitosan shell and a controllable positive zeta potential. The particles were stable in a pH range from 3.5 to 6.0 and lost stability after 14 days of storage in aqueous media. Due to the high positive surface charge of the particles, the innate properties of the polysaccharides used, and the harmless disassociation of the polyelectrolytes, we suggest that the development of these CS:Pec nanoparticles offers great promise as a chronic wound healing platform." @default.
• W2029721543 created "2016-06-24" @default.
• W2029721543 creator A5009871294 @default.
• W2029721543 creator A5068383294 @default.
• W2029721543 date "2014-03-17" @default.
• W2029721543 modified "2023-10-10" @default.
• W2029721543 title "Characterization of Self-Assembled Polyelectrolyte Complex Nanoparticles Formed from Chitosan and Pectin" @default.
• W2029721543 cites W1964914870 @default.
• W2029721543 cites W1967162280 @default.
• W2029721543 cites W1967344662 @default.
• W2029721543 cites W1975574581 @default.
• W2029721543 cites W1985974936 @default.
• W2029721543 cites W1999968637 @default.
• W2029721543 cites W2007489801 @default.
• W2029721543 cites W2008814769 @default.
• W2029721543 cites W2009448195 @default.
• W2029721543 cites W2011123063 @default.
• W2029721543 cites W2012897009 @default.
• W2029721543 cites W2017612727 @default.
• W2029721543 cites W2021084750 @default.
• W2029721543 cites W2025864326 @default.
• W2029721543 cites W2037717119 @default.
• W2029721543 cites W2038058861 @default.
• W2029721543 cites W2041716570 @default.
• W2029721543 cites W2044486914 @default.
• W2029721543 cites W2052850753 @default.
• W2029721543 cites W2057768542 @default.
• W2029721543 cites W2060545112 @default.
• W2029721543 cites W2060898975 @default.
• W2029721543 cites W2061073363 @default.
• W2029721543 cites W2063889759 @default.
• W2029721543 cites W2064864195 @default.
• W2029721543 cites W2071341169 @default.
• W2029721543 cites W2071772651 @default.
• W2029721543 cites W2076558842 @default.
• W2029721543 cites W2079822872 @default.
• W2029721543 cites W2080315164 @default.
• W2029721543 cites W2081376387 @default.
• W2029721543 cites W2085293124 @default.
• W2029721543 cites W2091651320 @default.
• W2029721543 cites W2094805298 @default.
• W2029721543 cites W2098656275 @default.
• W2029721543 cites W2103448406 @default.
• W2029721543 cites W2112469307 @default.
• W2029721543 cites W2135579715 @default.
• W2029721543 cites W2139381815 @default.
• W2029721543 cites W2148769448 @default.
• W2029721543 cites W2167516940 @default.
• W2029721543 cites W2170101626 @default.
• W2029721543 cites W2023511826 @default.
• W2029721543 doi "https://doi.org/10.1021/la500491c" @default.
• W2029721543 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/24593694" @default.
• W2029721543 hasPublicationYear "2014" @default.
• W2029721543 type Work @default.
• W2029721543 sameAs 2029721543 @default.
• W2029721543 citedByCount "98" @default.
• W2029721543 countsByYear W20297215432014 @default.
• W2029721543 countsByYear W20297215432015 @default.
• W2029721543 countsByYear W20297215432016 @default.
• W2029721543 countsByYear W20297215432017 @default.
• W2029721543 countsByYear W20297215432018 @default.
• W2029721543 countsByYear W20297215432019 @default.
• W2029721543 countsByYear W20297215432020 @default.
• W2029721543 countsByYear W20297215432021 @default.
• W2029721543 countsByYear W20297215432022 @default.
• W2029721543 countsByYear W20297215432023 @default.
• W2029721543 crossrefType "journal-article" @default.
• W2029721543 hasAuthorship W2029721543A5009871294 @default.
• W2029721543 hasAuthorship W2029721543A5068383294 @default.
• W2029721543 hasConcept C127413603 @default.
• W2029721543 hasConcept C147789679 @default.
• W2029721543 hasConcept C153356533 @default.
• W2029721543 hasConcept C155672457 @default.
• W2029721543 hasConcept C171250308 @default.
• W2029721543 hasConcept C178790620 @default.
• W2029721543 hasConcept C183882617 @default.
• W2029721543 hasConcept C184651966 @default.
• W2029721543 hasConcept C185592680 @default.
• W2029721543 hasConcept C187428577 @default.
• W2029721543 hasConcept C188027245 @default.
• W2029721543 hasConcept C192562407 @default.
• W2029721543 hasConcept C2779732960 @default.
• W2029721543 hasConcept C2780358262 @default.
• W2029721543 hasConcept C2780756937 @default.
• W2029721543 hasConcept C42360764 @default.
• W2029721543 hasConcept C521977710 @default.
• W2029721543 hasConcept C55493867 @default.
• W2029721543 hasConcept C86181022 @default.
• W2029721543 hasConceptScore W2029721543C127413603 @default.
• W2029721543 hasConceptScore W2029721543C147789679 @default.
• W2029721543 hasConceptScore W2029721543C153356533 @default.
• W2029721543 hasConceptScore W2029721543C155672457 @default.
• W2029721543 hasConceptScore W2029721543C171250308 @default.
• W2029721543 hasConceptScore W2029721543C178790620 @default.
• W2029721543 hasConceptScore W2029721543C183882617 @default.
• W2029721543 hasConceptScore W2029721543C184651966 @default.
• W2029721543 hasConceptScore W2029721543C185592680 @default.
• W2029721543 hasConceptScore W2029721543C187428577 @default.

• next