Matches in SemOpenAlex for { <https://semopenalex.org/work/W2029756987> ?p ?o ?g. }
Showing items 1 to 88 of
88
with 100 items per page.
- W2029756987 endingPage "79" @default.
- W2029756987 startingPage "77" @default.
- W2029756987 abstract "Fenobam is a clinically efficacious anxiolytic that acts as metabotropic glutamate receptor 5 (mGlu5) antagonist by binding to an allosteric site. Other mGlu5 receptor antagonists such as MPEP and MTEP bind to the same allosteric site and are efficacious in preclinical models of anxiety and depression. Consequently, the allosteric-binding site of the mGlu5 receptor is an attractive target for the discovery of novel psychiatric therapies. Radioligands of this binding site can be used for in vitro and in vivo pharmacodynamic studies. We report here a short synthesis of such a radioligand for the allosteric mGlu5 receptor-binding site, [3H]fenobam. Copyright © 2008 John Wiley & Sons, Ltd." @default.
- W2029756987 created "2016-06-24" @default.
- W2029756987 creator A5003131668 @default.
- W2029756987 creator A5004941560 @default.
- W2029756987 creator A5015411592 @default.
- W2029756987 creator A5078861377 @default.
- W2029756987 creator A5091124551 @default.
- W2029756987 date "2008-01-01" @default.
- W2029756987 modified "2023-09-25" @default.
- W2029756987 title "Synthesis of [3H]fenobam, a radioligand for the mGlu5 receptor" @default.
- W2029756987 cites W1972395466 @default.
- W2029756987 cites W1979594873 @default.
- W2029756987 cites W2004702080 @default.
- W2029756987 cites W2017866313 @default.
- W2029756987 cites W2025395364 @default.
- W2029756987 cites W2032142851 @default.
- W2029756987 cites W2051157148 @default.
- W2029756987 cites W2051752481 @default.
- W2029756987 cites W2061070984 @default.
- W2029756987 cites W2071203240 @default.
- W2029756987 cites W2072818925 @default.
- W2029756987 cites W2074562127 @default.
- W2029756987 cites W2081234982 @default.
- W2029756987 cites W2084903264 @default.
- W2029756987 cites W2089877233 @default.
- W2029756987 cites W2129134595 @default.
- W2029756987 doi "https://doi.org/10.1002/jlcr.1470" @default.
- W2029756987 hasPublicationYear "2008" @default.
- W2029756987 type Work @default.
- W2029756987 sameAs 2029756987 @default.
- W2029756987 citedByCount "0" @default.
- W2029756987 crossrefType "journal-article" @default.
- W2029756987 hasAuthorship W2029756987A5003131668 @default.
- W2029756987 hasAuthorship W2029756987A5004941560 @default.
- W2029756987 hasAuthorship W2029756987A5015411592 @default.
- W2029756987 hasAuthorship W2029756987A5078861377 @default.
- W2029756987 hasAuthorship W2029756987A5091124551 @default.
- W2029756987 hasConcept C107824862 @default.
- W2029756987 hasConcept C166342909 @default.
- W2029756987 hasConcept C170493617 @default.
- W2029756987 hasConcept C185592680 @default.
- W2029756987 hasConcept C26702167 @default.
- W2029756987 hasConcept C2776038425 @default.
- W2029756987 hasConcept C2777765862 @default.
- W2029756987 hasConcept C2909005528 @default.
- W2029756987 hasConcept C41653306 @default.
- W2029756987 hasConcept C49051014 @default.
- W2029756987 hasConcept C55493867 @default.
- W2029756987 hasConcept C61174792 @default.
- W2029756987 hasConcept C67847695 @default.
- W2029756987 hasConcept C71924100 @default.
- W2029756987 hasConcept C98274493 @default.
- W2029756987 hasConceptScore W2029756987C107824862 @default.
- W2029756987 hasConceptScore W2029756987C166342909 @default.
- W2029756987 hasConceptScore W2029756987C170493617 @default.
- W2029756987 hasConceptScore W2029756987C185592680 @default.
- W2029756987 hasConceptScore W2029756987C26702167 @default.
- W2029756987 hasConceptScore W2029756987C2776038425 @default.
- W2029756987 hasConceptScore W2029756987C2777765862 @default.
- W2029756987 hasConceptScore W2029756987C2909005528 @default.
- W2029756987 hasConceptScore W2029756987C41653306 @default.
- W2029756987 hasConceptScore W2029756987C49051014 @default.
- W2029756987 hasConceptScore W2029756987C55493867 @default.
- W2029756987 hasConceptScore W2029756987C61174792 @default.
- W2029756987 hasConceptScore W2029756987C67847695 @default.
- W2029756987 hasConceptScore W2029756987C71924100 @default.
- W2029756987 hasConceptScore W2029756987C98274493 @default.
- W2029756987 hasIssue "1" @default.
- W2029756987 hasLocation W20297569871 @default.
- W2029756987 hasOpenAccess W2029756987 @default.
- W2029756987 hasPrimaryLocation W20297569871 @default.
- W2029756987 hasRelatedWork W1246069513 @default.
- W2029756987 hasRelatedWork W2029756987 @default.
- W2029756987 hasRelatedWork W2075237700 @default.
- W2029756987 hasRelatedWork W2130605317 @default.
- W2029756987 hasRelatedWork W2145283218 @default.
- W2029756987 hasRelatedWork W2153401842 @default.
- W2029756987 hasRelatedWork W2180195230 @default.
- W2029756987 hasRelatedWork W2317524704 @default.
- W2029756987 hasRelatedWork W2319496949 @default.
- W2029756987 hasRelatedWork W2330872010 @default.
- W2029756987 hasVolume "51" @default.
- W2029756987 isParatext "false" @default.
- W2029756987 isRetracted "false" @default.
- W2029756987 magId "2029756987" @default.
- W2029756987 workType "article" @default.