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• W2029763634 abstract "En la práctica forense los marcadores del tipo STR (Short Tandem Repeat) son utilizados por su gran poder discriminativo y por ayudar a identificar individuos genéticamente. En Perú actualmente se utilizan como mínimo 20 STR.El objetivo del presente estudio es determinar las frecuencias alélicas de 21 marcadores genéticos de tipo STR (D3S1358, vWA, D16S539, CSF1PO, TPOX, D8S1179, D21S11, D18S51, D2S441, D19S433, TH01, FGA, D22S1045, D5S818, D13S317, D7S820, SE33, D10S1248, D1S1656, D12S391 y D2S1338) en una población mestiza peruana.Las frecuencias alélicas fueron obtenidas a partir de 300 individuos no emparentados provenientes de diferentes provincias del Perú. Con los datos obtenidos se realizó un análisis estadístico.Todos los loci, excepto el D10S1248 y el D2S1338, estuvieron en equilibrio de Hardy-Weinberg. El alelo más frecuente del marcador D3S1358 es el 15, con un 56,33% en la población peruana y un 34,65% en la población hispana, mientras que los alelos menos frecuentes en la población peruana son el 11 y el 19, y en la hispana es el alelo 9, que no posee la población peruana. El marcador vWA de la población peruana no posee los alelos 11, 12 y 17.3 que posee la población hispana. El PD es mayor de 0,9999999 y el PE es de 0,9999997. Al compararse las frecuencias alélicas de la población mestiza peruana y las frecuencias hispanas del manual de Globalfiler by Life Technologies For Forensic or Paternity 2013 se observan diferencias en las frecuencias alélicas de los marcadores.Short Tandem Repeat (STR) markers are used in forensic practice due to their great discriminative power and help to identify individuals genetically. At least 20 STRs are currently used in Peru.The objective of the present study is to determine the allelic frequencies of 21 genetic markers of type STR (D3S1358, vWA, D16S539, CSF1PO, TPOX, D8S1179, D21S11, D18S51, D2S441, D19S433, TH01, FGA, D22S1045, D5S818, D13S317, D7S820, SE33, D10S1248, D1S1656, D12S391 and D2S1338) in a mixed race Peruvian population.The allelic frequencies were obtained from 300 unrelated individuals from different provinces of Peru. A statistical analysis was performed on the data obtained.All loci, except for D10S1248 and D2S1338, were in Hardy-Weinberg equilibrium. The most frequent allele of the D3S1358 marker is 15, with 56.33% in the Peruvian population and with 34.65% in the Hispanic population, while the alleles less frequent in the Peruvian population were 11 and 19, and in the Hispanic one, it was the 9 allele, which the Peruvian population does not have. The vWA marker of the Peruvian population does not have the 11, 12, and 17.3 alleles seen in the Hispanic population. The PD is greater than 0.9999999 and the PE is 0.99999997. When comparing the allelic frequencies of the Peruvian mixed-race population and the Hispanic frequencies of the manual of Globalfiler by Life Technologies For Forensic or Paternity 2013, differences are observed in the allelic frequencies of the markers." @default.
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• W2029763634 date "2011-10-01" @default.
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• W2029763634 title "Hipoglucemias persistentes en paciente intervenida de cirugía bariátrica" @default.
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• W2029763634 doi "https://doi.org/10.1016/j.medcli.2011.01.001" @default.
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