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- W2029770010 abstract "Plasmids containing the origin of bidirectional replication (oriß) of the Chinese hamster dihydrofolate reductase-encoding gene (DHFR) were tested for autonomous replication in vivo and in vitro. The results show that plasmids pX24 and pneoS13, that contain a 4.8- and a 11.5-kb fragment, respectively, spanning the oriß region, are able to replicate autonomously in human cells and in a cell-free system that uses human cell extracts. Another plasmid, pX14, containing a 4.8-kb fragment that is immediately adjacent to the oriß region, also replicated in these two assays." @default.
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- W2029770010 title "Autonomous replication in vivo and in vitro of clones spanning the region of the DHFR origin of bidirectional replication (oriß)" @default.
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- W2029770010 doi "https://doi.org/10.1016/0378-1119(94)90670-x" @default.
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