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• W2029800274 endingPage "2686" @default.
• W2029800274 startingPage "2682" @default.
• W2029800274 abstract "In partially replicated T7 chromosomes, the points where parental strands are separating and new DNA is being synthesized can be seen in the electron microscope to contain regions of single-stranded template DNA. The single-stranded regions are located on only one of the two daughter arms of the replicating chromosome. Inman and Schnös observed such single-stranded regions in 50% of the growing points of replicating lambda DNA, and, as reported in this paper, we find them in about 85% of the growing points of T7 DNA. Both studies support the conclusion that DNA synthesis involves the direct elongation of one daughter strand in the growing point. Evidently, this elongation is accompanied by the unwinding of the parental double helix to expose a region of single-stranded DNA which is then converted to the duplex state by a discontinuous mechanism involving the synthesis of DNA fragments." @default.
• W2029800274 created "2016-06-24" @default.
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• W2029800274 date "1972-09-01" @default.
• W2029800274 modified "2023-09-26" @default.
• W2029800274 title "Regions of Single-Stranded DNA in the Growing Points of Replicating Bacteriophage T7 Chromosomes" @default.
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• W2029800274 doi "https://doi.org/10.1073/pnas.69.9.2682" @default.
• W2029800274 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/427016" @default.
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