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• W2029828633 abstract "With the successful testing of the immunosuppressive effects of cyclosporine in transplant patients in 1978, the field of organ transplants began an exponential growth. With that, the field of organ preservation became increasingly important as the need to increase preservation time and improve graft function became paramount. However, for every patient that receives a transplanted organ, there are 4 more on the waiting list. In addition, a patient dies from the lack of a transplant almost every 1½ hour. To alleviate this donor crisis, there is a need to expand the donor pool to marginal donor organs. The main reason these organs are underutilized is because the current method of static preservation, simple cold storage, is ineffective. This article will provide a general review of the methods of preservation including simple cold storage, hypothermic machine perfusion, normothermic machine perfusion, and oxygen persufflation. In addition, the article will provide a review of how these dynamic preservation methods have improved the recovery and preservation of marginal donor organs including donation after cardiac death and fatty livers." @default.
• W2029828633 created "2016-06-24" @default.
• W2029828633 creator A5057597151 @default.
• W2029828633 creator A5083369269 @default.
• W2029828633 date "2009-07-01" @default.
• W2029828633 modified "2023-10-17" @default.
• W2029828633 title "Preservation methods for kidney and liver" @default.
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• W2029828633 doi "https://doi.org/10.4161/org.5.3.9582" @default.
• W2029828633 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/2781089" @default.
• W2029828633 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/20046672" @default.
• W2029828633 hasPublicationYear "2009" @default.
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