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- W2029831470 abstract "After fusion of BHK cells with polyethylene glycol, the resulting syncitia contained in 77% of the cases multiple microtubule organizing centers (MTOCs), which were aggregated into a common centrosphere. Based on the observation of phagokinetic tracks, we found that the syncitia were able to locomote if (1) the MTOCs aggregated into a common centrosphere cluster, and (2) the clustered centrospheres were excluded from the cluster of nuclei of the syncitium. The results suggest that each individual pair of one nucleus and one centrosphere contributes, in a process of vectorial addition, its individual polarity to the polarity of the syneitium. Thus the widely accepted idea that the centrosphere is involved in the determinatinn of cell polarity can be generalized beyond the case of single cells." @default.
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- W2029831470 date "1987-01-01" @default.
- W2029831470 modified "2023-09-24" @default.
- W2029831470 title "Distribution of multiple centrospheres determines migration of BHK syncitia" @default.
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- W2029831470 doi "https://doi.org/10.1002/cm.970070310" @default.
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