FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2029837112> ?p ?o ?g. }

• W2029837112 endingPage "234" @default.
• W2029837112 startingPage "228" @default.
• W2029837112 abstract "The aim of our study was the long-term evolution of hepatitis B immunity and the titers of antibodies against the surface antigen (anti-HBs) acquired either naturally or after vaccination in hemodialysis (HD) patients with no history of hepatitis C virus (HCV) infection.36 HD patients were vaccinated with 4 doses of 40 microg recombinant B vaccine (Engerix, Rixensart, Belgium), intramuscularly at 0, 1, 2 and 6 months. 21 patients (60%) seroconverted developing anti-HBs titers > or = 10 IU/ml. Two patients were transferred to another unit before completion of 6 months after the last vaccine dose. We followed-up 19 HD patients who were immune against HBV after vaccination (Group A), and 30 immune patients (anti-HBs titers > or = 10 IU/ml) who had never been vaccinated and had antibodies against the core antigen (anti-HBc), diagnostic of natural HBV infection (Group B). In all patients of Groups A and B, anti-HBs were determined every 6 months, starting 6 months after the last dose in the vaccinated patients. Follow-up period lasted from October 2002 - April 2006.The mean follow-up in Group A was 21 +/- 12 months (range 6 - 36) and in Group B 29 +/- 12 months (range 6 - 42). Age, sex, presence of diabetes mellitus and duration of dialysis did not differ between the two groups. Five patients in Group A (26%) and 2 patients in Group B (9%) lost immunity (anti-HBs < 10 IU/ml) (p = 0.07). The median time to loss of immunity in Group A patients was 12 months (interquartile range 6 - 18 months), while in Group B patients it was 15 months (interquartile range 12 - 18 months). No booster dose was administered during the study. The 2 patients of Group B who lost immunity were the oldest of the group and redeveloped anti-HBs 6 and 12 months after they had lost it. During the first 6 months of the follow-up period, Group A had significantly higher anti-HBs titers than Group B (p < 0.05). However, this difference was lost later on, and after the first year of follow-up, anti-HBs titers were decreased significantly in Group A (p < 0.05), but remained unchanged in Group B throughout the follow-up period.In conclusion, HD patients lost hepatitis B immunity both after natural infection or vaccination, but naturally infected patients easily redeveloped protective anti-HBs titers. Anti-HBs titers decreased faster in vaccinated patients than in those with natural acquired immunity who held stable titers for a longer period. It is suggested that HD patients should be followed-up regularly for loss of HBV immunity after vaccination and receive a boosting dose when this occurs. In contrast, patients who acquired natural immunity do not need any anamnestic vaccination." @default.
• W2029837112 created "2016-06-24" @default.
• W2029837112 creator A5020295301 @default.
• W2029837112 creator A5022110405 @default.
• W2029837112 creator A5039654754 @default.
• W2029837112 creator A5041750232 @default.
• W2029837112 creator A5076942218 @default.
• W2029837112 creator A5086233413 @default.
• W2029837112 date "2007-10-01" @default.
• W2029837112 modified "2023-10-01" @default.
• W2029837112 title "Loss of hepatitis B immunity in hemodialysis patients acquired either naturally or after vaccination" @default.
• W2029837112 cites W2070350416 @default.
• W2029837112 cites W2104601436 @default.
• W2029837112 doi "https://doi.org/10.5414/cnp68228" @default.
• W2029837112 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/17969490" @default.
• W2029837112 hasPublicationYear "2007" @default.
• W2029837112 type Work @default.
• W2029837112 sameAs 2029837112 @default.
• W2029837112 citedByCount "52" @default.
• W2029837112 countsByYear W20298371122012 @default.
• W2029837112 countsByYear W20298371122013 @default.
• W2029837112 countsByYear W20298371122014 @default.
• W2029837112 countsByYear W20298371122015 @default.
• W2029837112 countsByYear W20298371122016 @default.
• W2029837112 countsByYear W20298371122017 @default.
• W2029837112 countsByYear W20298371122018 @default.
• W2029837112 countsByYear W20298371122019 @default.
• W2029837112 countsByYear W20298371122020 @default.
• W2029837112 countsByYear W20298371122021 @default.
• W2029837112 countsByYear W20298371122023 @default.
• W2029837112 crossrefType "journal-article" @default.
• W2029837112 hasAuthorship W2029837112A5020295301 @default.
• W2029837112 hasAuthorship W2029837112A5022110405 @default.
• W2029837112 hasAuthorship W2029837112A5039654754 @default.
• W2029837112 hasAuthorship W2029837112A5041750232 @default.
• W2029837112 hasAuthorship W2029837112A5076942218 @default.
• W2029837112 hasAuthorship W2029837112A5086233413 @default.
• W2029837112 hasConcept C126322002 @default.
• W2029837112 hasConcept C159654299 @default.
• W2029837112 hasConcept C203014093 @default.
• W2029837112 hasConcept C22070199 @default.
• W2029837112 hasConcept C2522874641 @default.
• W2029837112 hasConcept C2777382497 @default.
• W2029837112 hasConcept C2777410769 @default.
• W2029837112 hasConcept C2777785397 @default.
• W2029837112 hasConcept C2778063415 @default.
• W2029837112 hasConcept C2779341262 @default.
• W2029837112 hasConcept C2779978075 @default.
• W2029837112 hasConcept C2780593183 @default.
• W2029837112 hasConcept C2781037505 @default.
• W2029837112 hasConcept C32611913 @default.
• W2029837112 hasConcept C71924100 @default.
• W2029837112 hasConcept C8891405 @default.
• W2029837112 hasConcept C90924648 @default.
• W2029837112 hasConceptScore W2029837112C126322002 @default.
• W2029837112 hasConceptScore W2029837112C159654299 @default.
• W2029837112 hasConceptScore W2029837112C203014093 @default.
• W2029837112 hasConceptScore W2029837112C22070199 @default.
• W2029837112 hasConceptScore W2029837112C2522874641 @default.
• W2029837112 hasConceptScore W2029837112C2777382497 @default.
• W2029837112 hasConceptScore W2029837112C2777410769 @default.
• W2029837112 hasConceptScore W2029837112C2777785397 @default.
• W2029837112 hasConceptScore W2029837112C2778063415 @default.
• W2029837112 hasConceptScore W2029837112C2779341262 @default.
• W2029837112 hasConceptScore W2029837112C2779978075 @default.
• W2029837112 hasConceptScore W2029837112C2780593183 @default.
• W2029837112 hasConceptScore W2029837112C2781037505 @default.
• W2029837112 hasConceptScore W2029837112C32611913 @default.
• W2029837112 hasConceptScore W2029837112C71924100 @default.
• W2029837112 hasConceptScore W2029837112C8891405 @default.
• W2029837112 hasConceptScore W2029837112C90924648 @default.
• W2029837112 hasIssue "10" @default.
• W2029837112 hasLocation W20298371121 @default.
• W2029837112 hasLocation W20298371122 @default.
• W2029837112 hasOpenAccess W2029837112 @default.
• W2029837112 hasPrimaryLocation W20298371121 @default.
• W2029837112 hasRelatedWork W2057974065 @default.
• W2029837112 hasRelatedWork W2092044507 @default.
• W2029837112 hasRelatedWork W2103234787 @default.
• W2029837112 hasRelatedWork W2349110611 @default.
• W2029837112 hasRelatedWork W2352335052 @default.
• W2029837112 hasRelatedWork W2358397818 @default.
• W2029837112 hasRelatedWork W2385168807 @default.
• W2029837112 hasRelatedWork W3029705792 @default.
• W2029837112 hasRelatedWork W3185229370 @default.
• W2029837112 hasRelatedWork W4295886166 @default.
• W2029837112 hasVolume "68" @default.
• W2029837112 isParatext "false" @default.
• W2029837112 isRetracted "false" @default.
• W2029837112 magId "2029837112" @default.
• W2029837112 workType "article" @default.