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- W2029893872 abstract "Introduction: There are no reports to date on prevalence of extended-spectrum ˇ-lactamase (ESBL) producing strains in the UAE. The aim of this study was to evaluate the prevalence of extended-spectrum ˇ-lactamase producing E. coli and K. pneumoniae and MRSA in UAE. Methods: Retrospective analysis of microbiology laboratory data between January 2005 and 30 November 2006 was carried out. ESBL production was confirmed by double disk diffusion approximation test or by the combined disk method. Isolates from the same patient in one month and the same site of isolation with the same antimicrobial susceptibility were considered as duplicates and eliminated. The values for the year 2005 and 2006 were compared. Statistical analysis was carried out by SPSS software. Results: In 2005, 7.3% (64/883) of total E.coli isolates and 7.3% (21/286) of K. pneumoniae isolates were ESBL producers. In 2006 this value significantly increased for E. coli to 11.2% (96/854), while K. pneumoniae remained unchanged at 7.3% (20/276). Inpatient isolates were significantly higher than in outpatients. ESBL production in E.coli for outpatients increased from 4.15%(27/650) in 2005 to 6.91%(42/608) in 2006 (P = 0.043). There was a trend towards increasing ESBL production among inpatients for K. pneumoniae (9.8 to 14.2%) and for E. coli (15.9 to 22%). The MRSA rates for the years 2005 and 2006 were 6.7% (41/616) and 7.0% (34/484) respectively. There was no significant change in MRSA prevalence in inpatients (9 Vs. 10.7%) or outpatients (4.4 Vs. 4.5%). Conclusions: This study shows that there is a relatively high prevalence of ESBL E. coli and K. pneumoniae in our institution which is comparable to that reported from other countries in this region. This is likely driven by the unrestricted use of antimicrobials particularly 3rd generation cephalosporins. Antimicrobial stewardship programs and good infection control practices are required to stem the increasing resistance." @default.
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- W2029893872 date "2008-12-01" @default.
- W2029893872 modified "2023-09-26" @default.
- W2029893872 title "Survey of ESBL Producing Escherichia coli and Klebsiella pneumoniae and MRSA in a Tertiary Care Facility in United Arab Emirates" @default.
- W2029893872 doi "https://doi.org/10.1016/j.ijid.2008.05.296" @default.
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