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- W2029912103 abstract "We show how to use well-defined conjugated polyelectrolytes (CPEs) combined with surface energy patterning to fabricate DNA chips utilizing fluorescence signal amplification. Cholesterol-modified DNA strands in complex with a CPE are adsorbed to a surface energy pattern, formed by printing with soft elastomer stamps. Hybridization of the surface bound DNA strands with a short complementary strand from solution is monitored using both fluorescence microscopy and imaging surface plasmon resonance. The CPEs act as antennas, enhancing resonance energy transfer to the dye-labeled DNA when complementary hybridization of the double strand occurs." @default.
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- W2029912103 date "2009-12-08" @default.
- W2029912103 modified "2023-09-27" @default.
- W2029912103 title "DNA Chips with Conjugated Polyelectrolytes in Resonance Energy Transfer Mode" @default.
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- W2029912103 doi "https://doi.org/10.1021/la903101v" @default.
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