Matches in SemOpenAlex for { <https://semopenalex.org/work/W2029943325> ?p ?o ?g. }
- W2029943325 endingPage "85" @default.
- W2029943325 startingPage "78" @default.
- W2029943325 abstract "Several surgical procedures have been developed for reducing portal vein pressure to prevent postoperative liver injury. Nitric oxide synthase expression (NOS) induced by elevation of portal vein pressure is thought to play an important role in liver regeneration, but the details are not well understood.Rats in the control group and in the subcutaneous splenic transposition (SST) group underwent 90% partial hepatectomy. Survival and portal vein pressure were analyzed. The serum IL-6 and TNF-alpha levels were measured by enzyme-linked immunosorbent assay (ELISA). Hepatocyte proliferation and apoptosis 12 hours after hepatectomy were analyzed immunohistochemically. The protein and messenger RNA expression of inducible and endothelial NOS were analyzed using Western blotting and quantitative reverse transcriptase polymerase chain reaction, respectively.The survival rate of the SST group was significantly higher. Portal vein pressure, TNF-alpha level and the apoptotic index were significantly lower in the SST group. Twelve hours after surgery, liver inducible NOS (iNOS) protein expression was significantly lower in the SST group. However, protein expression of endothelial NOS was not significantly different between the groups.Inducible NOS expression after extended hepatectomy is related to the effects of porto-systemic shunting on the splanchnic circulation. Also, iNOS induction and concomitant nitric oxide generation appear to participate in the cytotoxicity of excessive portal pressure after extended hepatectomy." @default.
- W2029943325 created "2016-06-24" @default.
- W2029943325 creator A5008737850 @default.
- W2029943325 creator A5018150140 @default.
- W2029943325 creator A5024129680 @default.
- W2029943325 creator A5024644803 @default.
- W2029943325 creator A5047899621 @default.
- W2029943325 creator A5048730959 @default.
- W2029943325 creator A5062001972 @default.
- W2029943325 creator A5062724893 @default.
- W2029943325 creator A5073236797 @default.
- W2029943325 creator A5089204693 @default.
- W2029943325 date "2009-01-01" @default.
- W2029943325 modified "2023-09-24" @default.
- W2029943325 title "Effect of porto-systemic shunting on NOS expression after extended hepatectomy in rats" @default.
- W2029943325 cites W1972089133 @default.
- W2029943325 cites W1972191545 @default.
- W2029943325 cites W1981404338 @default.
- W2029943325 cites W2004047111 @default.
- W2029943325 cites W2014806005 @default.
- W2029943325 cites W2016893185 @default.
- W2029943325 cites W2021117769 @default.
- W2029943325 cites W2024741618 @default.
- W2029943325 cites W2031292559 @default.
- W2029943325 cites W2038310681 @default.
- W2029943325 cites W2046216474 @default.
- W2029943325 cites W2050215978 @default.
- W2029943325 cites W2059398903 @default.
- W2029943325 cites W2064553063 @default.
- W2029943325 cites W2068630823 @default.
- W2029943325 cites W2083655526 @default.
- W2029943325 cites W2086105281 @default.
- W2029943325 cites W2089390485 @default.
- W2029943325 cites W2093463196 @default.
- W2029943325 cites W2117774293 @default.
- W2029943325 cites W2130870274 @default.
- W2029943325 cites W2131249302 @default.
- W2029943325 cites W2152724821 @default.
- W2029943325 cites W2160993265 @default.
- W2029943325 cites W2312682792 @default.
- W2029943325 cites W4242788288 @default.
- W2029943325 cites W4251698976 @default.
- W2029943325 doi "https://doi.org/10.1111/j.1872-034x.2008.00404.x" @default.
- W2029943325 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/18713274" @default.
- W2029943325 hasPublicationYear "2009" @default.
- W2029943325 type Work @default.
- W2029943325 sameAs 2029943325 @default.
- W2029943325 citedByCount "3" @default.
- W2029943325 countsByYear W20299433252012 @default.
- W2029943325 countsByYear W20299433252015 @default.
- W2029943325 countsByYear W20299433252017 @default.
- W2029943325 crossrefType "journal-article" @default.
- W2029943325 hasAuthorship W2029943325A5008737850 @default.
- W2029943325 hasAuthorship W2029943325A5018150140 @default.
- W2029943325 hasAuthorship W2029943325A5024129680 @default.
- W2029943325 hasAuthorship W2029943325A5024644803 @default.
- W2029943325 hasAuthorship W2029943325A5047899621 @default.
- W2029943325 hasAuthorship W2029943325A5048730959 @default.
- W2029943325 hasAuthorship W2029943325A5062001972 @default.
- W2029943325 hasAuthorship W2029943325A5062724893 @default.
- W2029943325 hasAuthorship W2029943325A5073236797 @default.
- W2029943325 hasAuthorship W2029943325A5089204693 @default.
- W2029943325 hasConcept C104317684 @default.
- W2029943325 hasConcept C105580179 @default.
- W2029943325 hasConcept C126322002 @default.
- W2029943325 hasConcept C134018914 @default.
- W2029943325 hasConcept C141071460 @default.
- W2029943325 hasConcept C142724271 @default.
- W2029943325 hasConcept C159110652 @default.
- W2029943325 hasConcept C171056886 @default.
- W2029943325 hasConcept C17991360 @default.
- W2029943325 hasConcept C190283241 @default.
- W2029943325 hasConcept C2776795407 @default.
- W2029943325 hasConcept C2776909242 @default.
- W2029943325 hasConcept C2777214474 @default.
- W2029943325 hasConcept C2777622882 @default.
- W2029943325 hasConcept C2778808290 @default.
- W2029943325 hasConcept C519581460 @default.
- W2029943325 hasConcept C55493867 @default.
- W2029943325 hasConcept C56900294 @default.
- W2029943325 hasConcept C71924100 @default.
- W2029943325 hasConcept C85265743 @default.
- W2029943325 hasConcept C86803240 @default.
- W2029943325 hasConcept C95444343 @default.
- W2029943325 hasConceptScore W2029943325C104317684 @default.
- W2029943325 hasConceptScore W2029943325C105580179 @default.
- W2029943325 hasConceptScore W2029943325C126322002 @default.
- W2029943325 hasConceptScore W2029943325C134018914 @default.
- W2029943325 hasConceptScore W2029943325C141071460 @default.
- W2029943325 hasConceptScore W2029943325C142724271 @default.
- W2029943325 hasConceptScore W2029943325C159110652 @default.
- W2029943325 hasConceptScore W2029943325C171056886 @default.
- W2029943325 hasConceptScore W2029943325C17991360 @default.
- W2029943325 hasConceptScore W2029943325C190283241 @default.
- W2029943325 hasConceptScore W2029943325C2776795407 @default.
- W2029943325 hasConceptScore W2029943325C2776909242 @default.
- W2029943325 hasConceptScore W2029943325C2777214474 @default.
- W2029943325 hasConceptScore W2029943325C2777622882 @default.