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- W2029943952 abstract "Abstract The Whole Genome Sampling Analysis (WGSA) assay in combination with Affymetrix GeneChip Mapping Arrays is used for copy number analysis of high-quality DNA samples (i.e., samples that have been collected from blood, fresh or frozen tissue, or cell lines). Formalin-fixed, paraffin-embedded (FFPE) samples, however, represent the most prevalent form of archived clinical samples, but they provide additional challenges for molecular assays. FFPE processing usually results in the degradation of FFPE DNA and in the contamination and chemical modification of these DNA samples. In this article, we describe the steps needed to obtain reliable copy number predictions from degraded and contaminated FFPE samples." @default.
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- W2029943952 date "2012-11-01" @default.
- W2029943952 modified "2023-10-05" @default.
- W2029943952 title "Data Analysis Considerations for Detecting Copy Number Changes in Formalin-Fixed, Paraffin-Embedded Tissues" @default.
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- W2029943952 doi "https://doi.org/10.1101/pdb.ip071761" @default.
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