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• W2029944450 abstract "A high-resolution structure of the human MHC-I molecule HLA-A*1101 is presented in which it forms a complex with a sequence homologue of a peptide that occurs naturally in hepatitis B virus DNA polymerase. The sequence of the bound peptide is AIMPARFYPK, while that of the corresponding natural peptide is LIMPARFYPK. The peptide does not make efficient use of the middle E pocket for binding, which leads to a rather superficial and exposed binding mode for the central peptide residues. Despite this, the peptide binds with high affinity (IC50 of 31 nM)." @default.
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• W2029944450 date "2006-11-04" @default.
• W2029944450 modified "2023-10-18" @default.
• W2029944450 title "Structure of HLA-A*1101 in complex with a hepatitis B peptide homologue" @default.
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• W2029944450 doi "https://doi.org/10.1107/s1744309106044228" @default.
• W2029944450 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/2225367" @default.
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