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• W2029962318 abstract "Autoantibodies to the thyrotropin receptor (TSHR) can act as thyrotropin agonists or antagonists, or can cause thyroid hypertrophy. Neither the autoantibody-binding sites on the TSHR nor the intracellular mechanisms by which the autoantibodies mediate their u, erse functional effects are completely understood. This article reviews how cloning of the TSHR has contributed to our understanding of its structure and function, and has allowed induction of experimental autoimmunity to the TSHR." @default.
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• W2029962318 date "1997-09-01" @default.
• W2029962318 modified "2023-09-25" @default.
• W2029962318 title "Thyrotropin-receptor-mediated diseases: a paradigm for receptor autoimmunity" @default.
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• W2029962318 doi "https://doi.org/10.1016/s0167-5699(97)01089-x" @default.
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