Matches in SemOpenAlex for { <https://semopenalex.org/work/W2029969980> ?p ?o ?g. }
- W2029969980 endingPage "235" @default.
- W2029969980 startingPage "229" @default.
- W2029969980 abstract "Hypoxia induces survival signals in hepatocellular carcinoma (HCC). We attempted to find a hypoxia-induced signal that could be used for modulating HCC cell death. Cellular retinoic acid binding protein-II (CRABP-II) expression was significantly increased in hypoxic HCC cells. Treatment with retinoic acid (RA), a ligand for CRABP-II, induced HCC cell apoptosis more effectively in hypoxia than in normoxia, whereas hypoxia-induced CRABP-II expression attenuated RA-induced apoptosis. Inhibition of CRABP-II enhanced RA-induced apoptosis and sensitized RA-resistant HCC cells to RA cytotoxicity by attenuating p42/44 MAPK and Akt activation. Therefore, RA/CRABP-II signal modulation is therapeutically implicated in infiltrative HCCs exposed to hypoxia." @default.
- W2029969980 created "2016-06-24" @default.
- W2029969980 creator A5003213219 @default.
- W2029969980 creator A5012530895 @default.
- W2029969980 creator A5018763027 @default.
- W2029969980 creator A5024316231 @default.
- W2029969980 creator A5047347247 @default.
- W2029969980 creator A5059227237 @default.
- W2029969980 creator A5060122021 @default.
- W2029969980 creator A5062596225 @default.
- W2029969980 creator A5071607739 @default.
- W2029969980 creator A5088114646 @default.
- W2029969980 creator A5088914744 @default.
- W2029969980 creator A5089681505 @default.
- W2029969980 date "2010-09-01" @default.
- W2029969980 modified "2023-09-27" @default.
- W2029969980 title "Retinoic acid and its binding protein modulate apoptotic signals in hypoxic hepatocellular carcinoma cells" @default.
- W2029969980 cites W1554600230 @default.
- W2029969980 cites W1570165358 @default.
- W2029969980 cites W1587947784 @default.
- W2029969980 cites W175518023 @default.
- W2029969980 cites W1966165057 @default.
- W2029969980 cites W1978432350 @default.
- W2029969980 cites W1982893010 @default.
- W2029969980 cites W1990814766 @default.
- W2029969980 cites W1998626286 @default.
- W2029969980 cites W2011399707 @default.
- W2029969980 cites W2014591899 @default.
- W2029969980 cites W2016111230 @default.
- W2029969980 cites W2026951979 @default.
- W2029969980 cites W2029309859 @default.
- W2029969980 cites W2034822725 @default.
- W2029969980 cites W2040917386 @default.
- W2029969980 cites W2048805127 @default.
- W2029969980 cites W2062653631 @default.
- W2029969980 cites W2086857599 @default.
- W2029969980 cites W2120736516 @default.
- W2029969980 cites W2122256734 @default.
- W2029969980 cites W2126111825 @default.
- W2029969980 cites W2129286473 @default.
- W2029969980 cites W2133644385 @default.
- W2029969980 cites W2141478391 @default.
- W2029969980 cites W2146564308 @default.
- W2029969980 cites W2147681260 @default.
- W2029969980 cites W2152326461 @default.
- W2029969980 cites W2152398979 @default.
- W2029969980 cites W2153084734 @default.
- W2029969980 cites W2156877019 @default.
- W2029969980 cites W2157715173 @default.
- W2029969980 cites W2167813614 @default.
- W2029969980 cites W221467299 @default.
- W2029969980 cites W2226738742 @default.
- W2029969980 cites W2388163742 @default.
- W2029969980 cites W3023305311 @default.
- W2029969980 cites W4206026550 @default.
- W2029969980 cites W4242019232 @default.
- W2029969980 cites W58959379 @default.
- W2029969980 doi "https://doi.org/10.1016/j.canlet.2010.03.005" @default.
- W2029969980 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/20350780" @default.
- W2029969980 hasPublicationYear "2010" @default.
- W2029969980 type Work @default.
- W2029969980 sameAs 2029969980 @default.
- W2029969980 citedByCount "12" @default.
- W2029969980 countsByYear W20299699802012 @default.
- W2029969980 countsByYear W20299699802013 @default.
- W2029969980 countsByYear W20299699802015 @default.
- W2029969980 countsByYear W20299699802016 @default.
- W2029969980 countsByYear W20299699802018 @default.
- W2029969980 countsByYear W20299699802019 @default.
- W2029969980 countsByYear W20299699802022 @default.
- W2029969980 countsByYear W20299699802023 @default.
- W2029969980 crossrefType "journal-article" @default.
- W2029969980 hasAuthorship W2029969980A5003213219 @default.
- W2029969980 hasAuthorship W2029969980A5012530895 @default.
- W2029969980 hasAuthorship W2029969980A5018763027 @default.
- W2029969980 hasAuthorship W2029969980A5024316231 @default.
- W2029969980 hasAuthorship W2029969980A5047347247 @default.
- W2029969980 hasAuthorship W2029969980A5059227237 @default.
- W2029969980 hasAuthorship W2029969980A5060122021 @default.
- W2029969980 hasAuthorship W2029969980A5062596225 @default.
- W2029969980 hasAuthorship W2029969980A5071607739 @default.
- W2029969980 hasAuthorship W2029969980A5088114646 @default.
- W2029969980 hasAuthorship W2029969980A5088914744 @default.
- W2029969980 hasAuthorship W2029969980A5089681505 @default.
- W2029969980 hasConcept C120197328 @default.
- W2029969980 hasConcept C178790620 @default.
- W2029969980 hasConcept C185592680 @default.
- W2029969980 hasConcept C190283241 @default.
- W2029969980 hasConcept C2778019345 @default.
- W2029969980 hasConcept C2779314089 @default.
- W2029969980 hasConcept C2781121885 @default.
- W2029969980 hasConcept C31573885 @default.
- W2029969980 hasConcept C502942594 @default.
- W2029969980 hasConcept C540031477 @default.
- W2029969980 hasConcept C54355233 @default.
- W2029969980 hasConcept C55493867 @default.
- W2029969980 hasConcept C57074206 @default.
- W2029969980 hasConcept C62478195 @default.