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- W2029986357 abstract "Bile is the exocrine secretion of liver and synthesized by hepatocytes. It is drained into duodenum for the function ofdigestion or drained into gallbladder for of storage. Bile duct obstruction is a blockage in the tubes that carry bile to thegallbladder and small intestine. However, Bile duct ligation results in the changes of bile acids in serum, liver, urine, andfeces1, 2. In this work, we demonstrate a novel technique to image this pathological condition by using a newlydeveloped in vivo imaging system, which includes multiphoton microscopy and intravital hepatic imaging chamber. Theimages we acquired demonstrate the uptake, processing of 6-CFDA in hepatocytes and excretion of CF in the bilecanaliculi. In addition to imaging, we can also measure kinetics of the green fluorescence intensity." @default.
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- W2029986357 date "2008-02-07" @default.
- W2029986357 modified "2023-09-28" @default.
- W2029986357 title "In vivo multiphoton imaging of bile duct ligation" @default.
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- W2029986357 doi "https://doi.org/10.1117/12.764264" @default.
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