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- W2030098344 abstract "High plasma levels of low-density lipoprotein (LDL) cholesterol are a risk factor for the development of premature atherosclerosis. Direct adsorption of lipoproteins (DALI) is an apheresis technique by which LDL cholesterol is selectively removed from whole blood.The present study describes our experience with DALI LDL apheresis in severely hypercholesterolemic patients.Three hypercholesterolemic patients suffering from atherosclerotic complications were treated fortnightly by DALI apheresis, in a total of 308 sessions between December 2008 and January 2013. All patients were on the highest tolerated dose of statins and other lipid-lowering drugs.The sessions were essentially uneventful, adverse events being recorded in only 3.6% of them. A mean 63.3% acute reduction in LDL cholesterol was obtained.DALI apheresis proved to be a simple, safe and efficient method of lipid apheresis in hypercholesterolemic patients refractory to conservative lipid-lowering therapy." @default.
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- W2030098344 date "2015-03-01" @default.
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- W2030098344 title "LDL‐aférese no tratamento de hipercolesterolemia familiar: experiência do Hospital Santo António" @default.
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- W2030098344 doi "https://doi.org/10.1016/j.repc.2014.07.007" @default.
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