FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2030113165> ?p ?o ?g. }

• W2030113165 endingPage "S689" @default.
• W2030113165 startingPage "S688" @default.
• W2030113165 abstract "Lung stereotactic body radiation therapy (SBRT) is an effective treatment modality for early-stage non-small cell lung cancer (NSCLC). The utilization of intensity modulated radiation therapy (IMRT) in treatment planning allows for improved tumor coverage while sparing normal surrounding tissue. Volumetric treatments using an arc-based geometry can improve target coverage while sparing normal tissue compared to fixed gantry IMRT. The potential dosimetric benefits and limitation of SBRT in the treatment of peripheral lung lesions was compared between RapidArc (RA) and fixed gantry IMRT (FG-IMRT). Eight patients with peripheral lung lesions treated with SBRT according to an institutional protocol were reviewed. Comparison plans were generated using a volumetric single arc (Varian RapidArc) and FG-IMRT using Eclipse planning software. Seven non-coplanar fields were used in the fixed gantry plans. Lung lesions were prescribed 60 Gy in 5 fractions to cover 95% of the planning target volume (PTV). Attempts were made to adhere to the RTOG 0618 protocol for successful treatment planning. For the purposes of planning and monitor unit (MU) calculations, homogeneity corrections were not performed. Plans were analyzed in terms of conformality index (CI100%), homogeneity index as defined by D(5)/D(95) (HI), volume of 50% isodose to PTV volume (CI50%) to assess low dose spillage, and normal tissue constraints. The mean PTV volume was 68.67cc (SD +/-85.35). All patients planned with both treatment modalities met the RTOG criteria for target conformality. Mean target conformality (CI100%). The mean CI100% for RA and FG-IMRT was 1.02 and 1.04, respectively (p = 0.77). Although not significant, there was a trend toward improved low dose spillage with RA. The mean CI50% for RA and FG-IMRT was 4.41 and 5.07, respectively (p = 0.33). Mean plan homogeneity was improved with RA (HI = 1.06) compared to FG-IMRT (HI = 1.08, p = 0.02). The volume of lung receiving 20 Gy (V20) and 10 Gy (V10) was equivalent between treatment modalities. The V20 for RA and FG-IMRT was 6.25% and 7.11%, respectively (p = 0.64). The V10 for RA and FG-IMRT was 12.84% and 13.08%, respectively (p = 0.34). All other normal tissue constraints met the RTOG criteria. The number of monitor units (MU) for treatment delivery were equivalent between treatment modalities (p = 0.64). The treatment of peripheral lung lesions with SBRT using RA is dosimetrically equivalent to FG-IMRT. RA may provide an advantage to conventional IMRT by improving plan homogeneity. Also, low dose spillage trended toward improvement which may reduce the incidence of symptomatic radiation-induced pneumonitis." @default.
• W2030113165 created "2016-06-24" @default.
• W2030113165 creator A5001235172 @default.
• W2030113165 creator A5021479364 @default.
• W2030113165 creator A5022367698 @default.
• W2030113165 creator A5025195325 @default.
• W2030113165 creator A5031578112 @default.
• W2030113165 creator A5043045096 @default.
• W2030113165 creator A5052884545 @default.
• W2030113165 date "2009-11-01" @default.
• W2030113165 modified "2023-10-18" @default.
• W2030113165 title "Stereotactic Body Radiation Therapy (SBRT) using Intensity Modulation for Lung Tumors: A Planning Comparison of RapidArc and Static Fixed IMRT" @default.
• W2030113165 doi "https://doi.org/10.1016/j.ijrobp.2009.07.1570" @default.
• W2030113165 hasPublicationYear "2009" @default.
• W2030113165 type Work @default.
• W2030113165 sameAs 2030113165 @default.
• W2030113165 citedByCount "0" @default.
• W2030113165 crossrefType "journal-article" @default.
• W2030113165 hasAuthorship W2030113165A5001235172 @default.
• W2030113165 hasAuthorship W2030113165A5021479364 @default.
• W2030113165 hasAuthorship W2030113165A5022367698 @default.
• W2030113165 hasAuthorship W2030113165A5025195325 @default.
• W2030113165 hasAuthorship W2030113165A5031578112 @default.
• W2030113165 hasAuthorship W2030113165A5043045096 @default.
• W2030113165 hasAuthorship W2030113165A5052884545 @default.
• W2030113165 hasConcept C126322002 @default.
• W2030113165 hasConcept C126838900 @default.
• W2030113165 hasConcept C201645570 @default.
• W2030113165 hasConcept C2777714996 @default.
• W2030113165 hasConcept C2989005 @default.
• W2030113165 hasConcept C509974204 @default.
• W2030113165 hasConcept C71924100 @default.
• W2030113165 hasConceptScore W2030113165C126322002 @default.
• W2030113165 hasConceptScore W2030113165C126838900 @default.
• W2030113165 hasConceptScore W2030113165C201645570 @default.
• W2030113165 hasConceptScore W2030113165C2777714996 @default.
• W2030113165 hasConceptScore W2030113165C2989005 @default.
• W2030113165 hasConceptScore W2030113165C509974204 @default.
• W2030113165 hasConceptScore W2030113165C71924100 @default.
• W2030113165 hasIssue "3" @default.
• W2030113165 hasLocation W20301131651 @default.
• W2030113165 hasOpenAccess W2030113165 @default.
• W2030113165 hasPrimaryLocation W20301131651 @default.
• W2030113165 hasRelatedWork W2057960324 @default.
• W2030113165 hasRelatedWork W2363834598 @default.
• W2030113165 hasRelatedWork W2410379488 @default.
• W2030113165 hasRelatedWork W2800720255 @default.
• W2030113165 hasRelatedWork W2901599149 @default.
• W2030113165 hasRelatedWork W2980781247 @default.
• W2030113165 hasRelatedWork W3153034825 @default.
• W2030113165 hasRelatedWork W4237240905 @default.
• W2030113165 hasRelatedWork W4243045879 @default.
• W2030113165 hasRelatedWork W935391112 @default.
• W2030113165 hasVolume "75" @default.
• W2030113165 isParatext "false" @default.
• W2030113165 isRetracted "false" @default.
• W2030113165 magId "2030113165" @default.
• W2030113165 workType "article" @default.