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- W2030263599 abstract "There is widespread agreement on the need to integrate education in physical, mathematical, and life sciences. It is now feasible to create a ubiquitous learning and inquiry environment for providing a comprehensive introduction for biology to physical and mathematical scientists, which can be accessed from everywhere using a networked laptop. This paper proposes such an environment. The didactic portion is organized according to the flow of information among biomolecular systems, starting with the genome and continuing with the processes of transcription, translation, and post-translational modification, and the interaction of gene products to give rise to the cellular phenome and to interactions among cells. Reverse information flow via influence of the environment on the cell completes the information loop, with dynamic responses ranging in time scales from fractions of a second for an emergency response to thousands or millions of years for evolutionary change. The textbook level of understanding can be assembled from the NCBI bookshelf. The ability of students to dig deeper in all subjects is achieved through training in the use of Google Scholar and PubMed to assemble functional bibliographies beginning with seminal papers (early papers with many citations) leading up to the most recent advances, punctuated with review papers. Hands-on interaction with the concepts can be introduced with the use of bioinformatics and molecular modeling tools accessible online, leading to an early experience in computational research and in framing meaningful problems to be attacked experimentally. Physical and mathematical scientists also need an introduction to the granting systems in biology, by being guided through the grants and institutional databases other information at the NIH, NSF, DOE Office of Science, and foundations." @default.
- W2030263599 created "2016-06-24" @default.
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- W2030263599 date "2012-01-01" @default.
- W2030263599 modified "2023-09-27" @default.
- W2030263599 title "A Ubiquitous Learning Environment For Molecular Biology" @default.
- W2030263599 doi "https://doi.org/10.1016/j.bpj.2011.11.1151" @default.
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