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- W2030315058 abstract "An extracellular polysaccharide (EPS) from Phellinus igniarius was purified and characterized and its production investigated. The preferred culture conditions for EPS production were pH 6, temperature 28°C, with sucrose (35.40 g/L) and soy extract (2.58 g/L) as best carbon and nitrogen sources, respectively. The maximum EPS concentration was 1.549 g/L. Pure EPS was obtained from culture filtrates by size exclusion chromatography, and its molecular characteristics were examined using a multiangle laser-light scattering and refractive index detector system. The weight-average molar masses of the EPS was determined to be 3.430 × 105 g/mol. The molecular conformation of the EPS in aqueous solution was random coil. Furthermore, P. igniarius EPS could scavenge superoxide anion and hydroxyl radicals. The antitumor activity of EPS reached 6.79% at an EPS concentration of 200 μg/mL. These results show the great potential for EPS to be used in the pharmacological industry in place of synthetic compounds." @default.
- W2030315058 created "2016-06-24" @default.
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- W2030315058 date "2012-02-21" @default.
- W2030315058 modified "2023-10-14" @default.
- W2030315058 title "Purification, characterization and bioactivity of an extracellular polysaccharide produced from Phellinus igniarius" @default.
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- W2030315058 doi "https://doi.org/10.1007/s13213-012-0427-6" @default.
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