Matches in SemOpenAlex for { <https://semopenalex.org/work/W2030347861> ?p ?o ?g. }
- W2030347861 endingPage "627" @default.
- W2030347861 startingPage "621" @default.
- W2030347861 abstract "In order to gain further insight on the role of Kaposi's sarcoma-associated herpesvirus (KSHV) in classic and endemic Kaposi's sarcoma (KS) pathogenesis, we aimed to determine (i) whether KSHV is detectable in peripheral blood mononuclear cells (PBMCs), (ii) which PBMCs subpopulation harbor the virus, (iii) which clinical, histologic, and immunologic parameters are associated with KSHV viremia in a population of classic and endemic KS. KSHV viremia and various immunologic parameters were screened on 81 patients. KSHV viremia was positive in 58% of the patients. KSHV was detected in B cells, T cells, and monocytes. CD34+ cells depleted in circulating endothelial cells (CECs) were never infected and 50% of the patients tested had CECs infected by KSHV. We observed a significant increase of IL-2 and IFN-gamma production by CD4 T cells and an increase of IFN-gamma production by CD8 T cells compared to control patients. KS progression (P = 0.001) and KS staging (P = 0.03) were significantly and independently associated with positive KSHV viremia. Our results show that there is no specific immunosuppression in classic or endemic KS. We showed that KSHV can be detected within CECs and that KSHV viremia could be an indicator of circulating mature or precursor spindle cells." @default.
- W2030347861 created "2016-06-24" @default.
- W2030347861 creator A5003048807 @default.
- W2030347861 creator A5004905312 @default.
- W2030347861 creator A5007042449 @default.
- W2030347861 creator A5025478490 @default.
- W2030347861 creator A5030730409 @default.
- W2030347861 creator A5035640410 @default.
- W2030347861 creator A5037325057 @default.
- W2030347861 creator A5037376216 @default.
- W2030347861 creator A5058530792 @default.
- W2030347861 creator A5063455000 @default.
- W2030347861 creator A5063765737 @default.
- W2030347861 creator A5081977456 @default.
- W2030347861 creator A5083772972 @default.
- W2030347861 creator A5088319976 @default.
- W2030347861 date "2006-03-01" @default.
- W2030347861 modified "2023-10-17" @default.
- W2030347861 title "Kaposi's Sarcoma-Associated Herpesvirus Viremia is Associated with the Progression of Classic and Endemic Kaposi's Sarcoma" @default.
- W2030347861 cites W1492343766 @default.
- W2030347861 cites W1544270898 @default.
- W2030347861 cites W1594911052 @default.
- W2030347861 cites W1962046702 @default.
- W2030347861 cites W1970339166 @default.
- W2030347861 cites W1977500292 @default.
- W2030347861 cites W1982778833 @default.
- W2030347861 cites W1986075828 @default.
- W2030347861 cites W1992258294 @default.
- W2030347861 cites W2000019998 @default.
- W2030347861 cites W2006040110 @default.
- W2030347861 cites W2007444961 @default.
- W2030347861 cites W2009808922 @default.
- W2030347861 cites W2014571799 @default.
- W2030347861 cites W2019745410 @default.
- W2030347861 cites W2032438721 @default.
- W2030347861 cites W2038621149 @default.
- W2030347861 cites W2045148822 @default.
- W2030347861 cites W2046245571 @default.
- W2030347861 cites W2052604523 @default.
- W2030347861 cites W2053901884 @default.
- W2030347861 cites W2066250170 @default.
- W2030347861 cites W2071969046 @default.
- W2030347861 cites W2075895818 @default.
- W2030347861 cites W2078387689 @default.
- W2030347861 cites W2081651119 @default.
- W2030347861 cites W2118314453 @default.
- W2030347861 cites W2123551649 @default.
- W2030347861 cites W2123830992 @default.
- W2030347861 cites W2125022232 @default.
- W2030347861 cites W2127576962 @default.
- W2030347861 cites W2145524503 @default.
- W2030347861 cites W2149010083 @default.
- W2030347861 cites W2149204478 @default.
- W2030347861 cites W2168833761 @default.
- W2030347861 cites W2257453531 @default.
- W2030347861 cites W2401183309 @default.
- W2030347861 cites W2405751828 @default.
- W2030347861 cites W4235116950 @default.
- W2030347861 doi "https://doi.org/10.1038/sj.jid.5700083" @default.
- W2030347861 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/16410791" @default.
- W2030347861 hasPublicationYear "2006" @default.
- W2030347861 type Work @default.
- W2030347861 sameAs 2030347861 @default.
- W2030347861 citedByCount "61" @default.
- W2030347861 countsByYear W20303478612012 @default.
- W2030347861 countsByYear W20303478612013 @default.
- W2030347861 countsByYear W20303478612014 @default.
- W2030347861 countsByYear W20303478612015 @default.
- W2030347861 countsByYear W20303478612016 @default.
- W2030347861 countsByYear W20303478612017 @default.
- W2030347861 countsByYear W20303478612018 @default.
- W2030347861 countsByYear W20303478612019 @default.
- W2030347861 countsByYear W20303478612020 @default.
- W2030347861 countsByYear W20303478612021 @default.
- W2030347861 countsByYear W20303478612022 @default.
- W2030347861 countsByYear W20303478612023 @default.
- W2030347861 crossrefType "journal-article" @default.
- W2030347861 hasAuthorship W2030347861A5003048807 @default.
- W2030347861 hasAuthorship W2030347861A5004905312 @default.
- W2030347861 hasAuthorship W2030347861A5007042449 @default.
- W2030347861 hasAuthorship W2030347861A5025478490 @default.
- W2030347861 hasAuthorship W2030347861A5030730409 @default.
- W2030347861 hasAuthorship W2030347861A5035640410 @default.
- W2030347861 hasAuthorship W2030347861A5037325057 @default.
- W2030347861 hasAuthorship W2030347861A5037376216 @default.
- W2030347861 hasAuthorship W2030347861A5058530792 @default.
- W2030347861 hasAuthorship W2030347861A5063455000 @default.
- W2030347861 hasAuthorship W2030347861A5063765737 @default.
- W2030347861 hasAuthorship W2030347861A5081977456 @default.
- W2030347861 hasAuthorship W2030347861A5083772972 @default.
- W2030347861 hasAuthorship W2030347861A5088319976 @default.
- W2030347861 hasBestOaLocation W20303478611 @default.
- W2030347861 hasConcept C137061746 @default.
- W2030347861 hasConcept C142724271 @default.
- W2030347861 hasConcept C159047783 @default.
- W2030347861 hasConcept C167672396 @default.
- W2030347861 hasConcept C202751555 @default.
- W2030347861 hasConcept C203014093 @default.