Matches in SemOpenAlex for { <https://semopenalex.org/work/W2030348537> ?p ?o ?g. }
Showing items 1 to 86 of
86
with 100 items per page.
- W2030348537 endingPage "550" @default.
- W2030348537 startingPage "544" @default.
- W2030348537 abstract "Valorar el cumplimiento terapéutico del tratamiento con inhibidores del sistema renina-angiotensina (inhibidores de la enzima de conversión de la angiotensina o antagonistas de los receptores de la angiotensina II) en la hipertensión arterial no controlada de pacientes de alto riesgo vascular. Estudio prospectivo, longitudinal y multicéntrico desarrollado en 102 centros de atención primaria españoles. Se incluyó a 808 hipertensos tratados con inhibidores del sistema renina-angiotensina (inhibidores de la enzima de conversión de la angiotensina o antagonistas de los receptores de la angiotensina II), no controlados y con alto riesgo vascular. Se realizaron cuatro visitas (inicial y tras 1, 3 y 6 meses). Se midió el cumplimiento mediante monitores electrónicos. Se calculó el porcentaje de cumplimiento medio, el porcentaje de cumplidores en general, cumplidores de una toma diaria, cumplidores en horario correcto y cobertura antihipertensiva. Se consideró cumplidor a aquel cuya tasa de cumplimiento estuviera entre el 80 y el 100%. Finalizaron el estudio 701 pacientes (media de edad, 63,7 ± 11,1 años). Las presiones arteriales sistólicas y diastólicas se redujeron significativamente (p < 0,0001): 18,8 y 9,8 mmHg respectivamente. Los controlados fueron el 70% (intervalo de confianza del 95%, 65,6-74,4%). Se observaron diferencias significativas con mayor control entre los cumplidores que entre los incumplidores (p < 0,05). La media del porcentaje de dosis tomadas fue del 87,9% (intervalo de confianza del 95%, 84,8-91%) y la cobertura terapéutica, el 82,4% (intervalo de confianza del 95%, 78,7-86,1%). Fueron cumplidores en general el 73,3% (intervalo de confianza del 95%, 69-77,6%); de una toma diaria, el 52,8% (intervalo de confianza del 95%, 48-57,6%), y en horario correcto, el 46,5% (intervalo de confianza del 95%, 41,9-51,1%). El cumplimiento se asoció a menor número de fármacos prescritos y no estar diagnosticado de diabetes (p < 0,001). Entre los hipertensos de alto riesgo vascular, el incumplimiento fue muy alto, fundamentalmente cuando toman cinco o más comprimidos diarios. To assess compliance with treatment inhibit the renin-angiotensin system (angiotensin-converting enzyme inhibitors or angiotensin receptor blockers) in uncontrolled hypertension in patients at high cardiovascular risk. Prospective, longitudinal, multicenter study, carried out in 102 Spanish primary care centers. We included 808 uncontrolled hypertensive patients treated with angiotensin-converting enzyme inhibitors or angiotensin receptor blockers who were at high vascular risk; 4 visits were conducted: baseline and 1, 3, and 6 months later. Compliance was measured by electronic monitors. We calculated the mean percentage compliance, the overall percentage of compliers, once-daily compliers, compliers with the prescribed time frame, and antihypertensive coverage. We considered a patient to be a complier when the percentage compliance was 80%-100%. In all, 701 patients completed the study (mean age, 63.7 [11.1] years). The systolic and diastolic blood pressures decreased significantly (P<.0001) to 18.8 mmHg and 9.8 mmHg, respectively. The control rate was 70% (95% confidence interval, 65.6%-74.4%) (P=.0001). The rate of control was significantly higher among compliers than noncompliers (P<.05). The mean percentage of doses taken was 87.9% (95% confidence interval, 84.8%-91%) and the mean therapeutic coverage was 82.4% (95% confidence interval, 78.7%-86.1%). Overall, 73.3% of the patients were compliers (95% confidence interval, 69%-77.6%), 52.8% (95% confidence interval, 48%-57.6%) were once-daily compliers, and 46.5% (95% confidence interval, 41.9%-51.1%) complied with the prescribed time frame. Noncompliance was associated with a higher number of drugs prescribed (P<.001). In hypertensive patients at high vascular risk, the rate of therapeutic noncompliance was very high, mainly when they took 5 or more pills daily. Full English text available from: www.revespcardiol.org" @default.
- W2030348537 created "2016-06-24" @default.
- W2030348537 creator A5014656891 @default.
- W2030348537 creator A5037855548 @default.
- W2030348537 creator A5038191900 @default.
- W2030348537 creator A5040578767 @default.
- W2030348537 creator A5059304688 @default.
- W2030348537 creator A5074374690 @default.
- W2030348537 creator A5080131319 @default.
- W2030348537 creator A5090248749 @default.
- W2030348537 date "2012-06-01" @default.
- W2030348537 modified "2023-10-18" @default.
- W2030348537 title "¿Los pacientes con alto riesgo vascular toman correctamente la medicación antihipertensiva? Estudio Cumple-MEMS" @default.
- W2030348537 cites W1981993792 @default.
- W2030348537 cites W1983783021 @default.
- W2030348537 cites W1986957523 @default.
- W2030348537 cites W1988517264 @default.
- W2030348537 cites W2006962910 @default.
- W2030348537 cites W2019044882 @default.
- W2030348537 cites W2020971129 @default.
- W2030348537 cites W2034696263 @default.
- W2030348537 cites W2042230393 @default.
- W2030348537 cites W2046751682 @default.
- W2030348537 cites W2053738735 @default.
- W2030348537 cites W2054956235 @default.
- W2030348537 cites W2058749856 @default.
- W2030348537 cites W2063396650 @default.
- W2030348537 cites W2087180130 @default.
- W2030348537 cites W2105281538 @default.
- W2030348537 cites W2137665561 @default.
- W2030348537 cites W2146568526 @default.
- W2030348537 cites W2158717000 @default.
- W2030348537 cites W2172197118 @default.
- W2030348537 cites W2313754305 @default.
- W2030348537 cites W3034899365 @default.
- W2030348537 cites W4245627694 @default.
- W2030348537 cites W4248909291 @default.
- W2030348537 doi "https://doi.org/10.1016/j.recesp.2012.01.018" @default.
- W2030348537 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/22520867" @default.
- W2030348537 hasPublicationYear "2012" @default.
- W2030348537 type Work @default.
- W2030348537 sameAs 2030348537 @default.
- W2030348537 citedByCount "21" @default.
- W2030348537 countsByYear W20303485372012 @default.
- W2030348537 countsByYear W20303485372013 @default.
- W2030348537 countsByYear W20303485372014 @default.
- W2030348537 countsByYear W20303485372015 @default.
- W2030348537 countsByYear W20303485372016 @default.
- W2030348537 countsByYear W20303485372017 @default.
- W2030348537 countsByYear W20303485372018 @default.
- W2030348537 countsByYear W20303485372022 @default.
- W2030348537 crossrefType "journal-article" @default.
- W2030348537 hasAuthorship W2030348537A5014656891 @default.
- W2030348537 hasAuthorship W2030348537A5037855548 @default.
- W2030348537 hasAuthorship W2030348537A5038191900 @default.
- W2030348537 hasAuthorship W2030348537A5040578767 @default.
- W2030348537 hasAuthorship W2030348537A5059304688 @default.
- W2030348537 hasAuthorship W2030348537A5074374690 @default.
- W2030348537 hasAuthorship W2030348537A5080131319 @default.
- W2030348537 hasAuthorship W2030348537A5090248749 @default.
- W2030348537 hasConcept C29456083 @default.
- W2030348537 hasConcept C71924100 @default.
- W2030348537 hasConceptScore W2030348537C29456083 @default.
- W2030348537 hasConceptScore W2030348537C71924100 @default.
- W2030348537 hasIssue "6" @default.
- W2030348537 hasLocation W20303485371 @default.
- W2030348537 hasLocation W20303485372 @default.
- W2030348537 hasOpenAccess W2030348537 @default.
- W2030348537 hasPrimaryLocation W20303485371 @default.
- W2030348537 hasRelatedWork W1506200166 @default.
- W2030348537 hasRelatedWork W1995515455 @default.
- W2030348537 hasRelatedWork W1999344589 @default.
- W2030348537 hasRelatedWork W2039318446 @default.
- W2030348537 hasRelatedWork W2080531066 @default.
- W2030348537 hasRelatedWork W2748952813 @default.
- W2030348537 hasRelatedWork W2789448498 @default.
- W2030348537 hasRelatedWork W2899084033 @default.
- W2030348537 hasRelatedWork W3032375762 @default.
- W2030348537 hasRelatedWork W3108674512 @default.
- W2030348537 hasVolume "65" @default.
- W2030348537 isParatext "false" @default.
- W2030348537 isRetracted "false" @default.
- W2030348537 magId "2030348537" @default.
- W2030348537 workType "article" @default.