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• W2030355346 abstract "During the course of drug metabolism studies, a major metabolite of compound 1 was detected in rhesus monkeys and assigned structure 4. The intriguing biotransformation of 1 leading to 4 was confirmed by a 19-step total synthesis starting from resorcinol (11), the key feature of which was the construction of the oxygen bridge utilizing a phenolic oxidation and trapping sequence. In addition, the synthesis of a related metabolite (5) is described." @default.
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• W2030355346 date "2005-01-05" @default.
• W2030355346 modified "2023-09-23" @default.
• W2030355346 title "Estrogen Receptor Ligands. 12. Synthesis of the Major Metabolites of an ERα-Selective, Dihydrobenzoxathiin Antagonist for Osteoporosis" @default.
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• W2030355346 doi "https://doi.org/10.1021/ol047741f" @default.
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