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• W2030355915 endingPage "1062" @default.
• W2030355915 startingPage "1053" @default.
• W2030355915 abstract "A series of near-diploid embryonal carcinoma-like hybrid cells were obtained from polyethylene glycol mediated cell fusion between murine embryonal carcinoma cells (PSA-6TG1 or OTF9-63) having one X chromosome and thymocytes or bone marrow cells from female mice carrying Cattanach's or Searle's translocation. Prior to fusion with EC cells the somatic cells are presumed to contain only one active X chromosome. Following hybrid formation, the chronology of X chromosome replication and the expression of X-linked gene Pgk-1 indicated that all X chromosomes contributed by both parents were active in these hybrids. Experiments were performed to rule out the possibility that the hybrids were formed by fusion of EC cells with rare somatic cells in which both X chromosomes were active. Taken together the data indicate that within four days of fusion there is reactivation of the entire inactive X chromosome." @default.
• W2030355915 created "2016-06-24" @default.
• W2030355915 creator A5047791990 @default.
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• W2030355915 creator A5091161390 @default.
• W2030355915 date "1983-10-01" @default.
• W2030355915 modified "2023-10-18" @default.
• W2030355915 title "Reversal of X-inactivation in female mouse somatic cells hybridized with murine teratocarcinoma stem cells in vitro" @default.
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• W2030355915 doi "https://doi.org/10.1016/0092-8674(83)90563-9" @default.
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