FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2030372916> ?p ?o ?g. }

• W2030372916 endingPage "4983" @default.
• W2030372916 startingPage "4979" @default.
• W2030372916 abstract "A cDNA clone encoding CENP-B, the 80-kDa human centromere autoantigen, was used to construct a panel of hybrid proteins containing four different regions of CENP-B. These have allowed us to identify three independent epitopes on CENP-B that are targets of autoantibodies. Two of these are recognized concurrently in greater than or equal to 90% of patient sera containing anticentromere autoantibodies (ACA), conclusively demonstrating that this autoimmune response is polyclonal. When present and previous data are combined, ACA are shown to recognize at least five independent epitopes on CENP-B. A radioimmunoassay based on cloned CENP-B has demonstrated that sera from greater than or equal to 96% of patients with ACA recognize the cloned antigen, thus defining a region of the protein that is recognized by virtually all patients with ACA. These findings have significant implications for models that seek to explain the origin of ACA and for the future detection of this group of autoantibodies in the clinical setting." @default.
• W2030372916 created "2016-06-24" @default.
• W2030372916 creator A5008986753 @default.
• W2030372916 creator A5033998542 @default.
• W2030372916 creator A5047873642 @default.
• W2030372916 creator A5079615188 @default.
• W2030372916 creator A5086838203 @default.
• W2030372916 date "1987-07-01" @default.
• W2030372916 modified "2023-09-27" @default.
• W2030372916 title "Analysis of anticentromere autoantibodies using cloned autoantigen CENP-B." @default.
• W2030372916 cites W1481275674 @default.
• W2030372916 cites W1518613272 @default.
• W2030372916 cites W1554817242 @default.
• W2030372916 cites W160997634 @default.
• W2030372916 cites W1898939379 @default.
• W2030372916 cites W1977209683 @default.
• W2030372916 cites W1987899138 @default.
• W2030372916 cites W1999861460 @default.
• W2030372916 cites W2000231159 @default.
• W2030372916 cites W2002027999 @default.
• W2030372916 cites W2011486018 @default.
• W2030372916 cites W2012847227 @default.
• W2030372916 cites W2018289835 @default.
• W2030372916 cites W2025973568 @default.
• W2030372916 cites W2035653882 @default.
• W2030372916 cites W2062719651 @default.
• W2030372916 cites W2068032875 @default.
• W2030372916 cites W2072482106 @default.
• W2030372916 cites W2073898388 @default.
• W2030372916 cites W2080795403 @default.
• W2030372916 cites W2081761746 @default.
• W2030372916 cites W2082995756 @default.
• W2030372916 cites W2095868332 @default.
• W2030372916 cites W2101108802 @default.
• W2030372916 cites W2138830547 @default.
• W2030372916 cites W2139736965 @default.
• W2030372916 cites W2150392258 @default.
• W2030372916 cites W2153709755 @default.
• W2030372916 cites W2162737474 @default.
• W2030372916 cites W2165449027 @default.
• W2030372916 cites W2472254266 @default.
• W2030372916 cites W44053923 @default.
• W2030372916 doi "https://doi.org/10.1073/pnas.84.14.4979" @default.
• W2030372916 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/305230" @default.
• W2030372916 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/2440036" @default.
• W2030372916 hasPublicationYear "1987" @default.
• W2030372916 type Work @default.
• W2030372916 sameAs 2030372916 @default.
• W2030372916 citedByCount "87" @default.
• W2030372916 countsByYear W20303729162012 @default.
• W2030372916 countsByYear W20303729162013 @default.
• W2030372916 countsByYear W20303729162014 @default.
• W2030372916 countsByYear W20303729162015 @default.
• W2030372916 countsByYear W20303729162016 @default.
• W2030372916 countsByYear W20303729162017 @default.
• W2030372916 countsByYear W20303729162018 @default.
• W2030372916 countsByYear W20303729162019 @default.
• W2030372916 countsByYear W20303729162020 @default.
• W2030372916 countsByYear W20303729162021 @default.
• W2030372916 countsByYear W20303729162022 @default.
• W2030372916 countsByYear W20303729162023 @default.
• W2030372916 crossrefType "journal-article" @default.
• W2030372916 hasAuthorship W2030372916A5008986753 @default.
• W2030372916 hasAuthorship W2030372916A5033998542 @default.
• W2030372916 hasAuthorship W2030372916A5047873642 @default.
• W2030372916 hasAuthorship W2030372916A5079615188 @default.
• W2030372916 hasAuthorship W2030372916A5086838203 @default.
• W2030372916 hasBestOaLocation W20303729162 @default.
• W2030372916 hasConcept C104317684 @default.
• W2030372916 hasConcept C121050878 @default.
• W2030372916 hasConcept C134018914 @default.
• W2030372916 hasConcept C141440757 @default.
• W2030372916 hasConcept C147483822 @default.
• W2030372916 hasConcept C153911025 @default.
• W2030372916 hasConcept C157695867 @default.
• W2030372916 hasConcept C159654299 @default.
• W2030372916 hasConcept C163764329 @default.
• W2030372916 hasConcept C176685330 @default.
• W2030372916 hasConcept C187882448 @default.
• W2030372916 hasConcept C189482833 @default.
• W2030372916 hasConcept C195616568 @default.
• W2030372916 hasConcept C199360897 @default.
• W2030372916 hasConcept C203014093 @default.
• W2030372916 hasConcept C2778453870 @default.
• W2030372916 hasConcept C41008148 @default.
• W2030372916 hasConcept C54355233 @default.
• W2030372916 hasConcept C70721500 @default.
• W2030372916 hasConcept C81089528 @default.
• W2030372916 hasConcept C86803240 @default.
• W2030372916 hasConcept C956191 @default.
• W2030372916 hasConceptScore W2030372916C104317684 @default.
• W2030372916 hasConceptScore W2030372916C121050878 @default.
• W2030372916 hasConceptScore W2030372916C134018914 @default.
• W2030372916 hasConceptScore W2030372916C141440757 @default.
• W2030372916 hasConceptScore W2030372916C147483822 @default.
• W2030372916 hasConceptScore W2030372916C153911025 @default.
• W2030372916 hasConceptScore W2030372916C157695867 @default.
• W2030372916 hasConceptScore W2030372916C159654299 @default.

• next