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- W2030378687 abstract "Abstract. The low molecular weight form of insulin-like growth factor binding protein (35 kD IGFBP), determined in serum by radioimmunoassay during non-fasting conditions, was high at birth and declined with increasing age during childhood and adolescence (N = 149). Inverse correlation was found between chronological age and 35 kD IGFBP values (r = −0.61, P < 0.001) during childhood and adolescence, but no age dependency was found in adult subjects aged 20–66 years (N = 73). The mean and 95% confidence limits of immunoreactive 35 kD IGFBP were 34 μg/l and 15–79 μg/l, respectively, in healthy adults (N = 73) in whom the blood samples were drawn after a one-night fast. The mean level of the 35 kD IGFBP in patients with acromegaly (19 μg/l, N = 23) was decreased by 50% in comparison with healthy adults, whereas a 2-fold elevation of the mean levels was found in both anorexia nervosa patients (70 μg/l, N = 13) and adult patients with GH deficiency (69 μg/l, N = 22). In patients with anorexia nervosa, the 35 kD IGFBP levels were inversely related to the body mass index (r = −0.65, P < 0.02)." @default.
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- W2030378687 date "1988-07-01" @default.
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- W2030378687 title "Serum levels of the low molecular weight form of insulin-like growth factor binding protein in healthy subjects and patients with growth hormone deficiency, acromegaly and anorexia nervosa" @default.
- W2030378687 doi "https://doi.org/10.1530/acta.0.1180321" @default.
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