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• W2030405113 abstract "The immune system retains memory of current and past infections and can sense the presence of cancer by elaborating autoantibodies to tumor proteins. In the presence of an autoimmune disease, the immune system is an efficient, natural biosensor. Therefore we exploit the immune system through a high-throughput process to isolate disease-specific epitopes for diagnostic and therapeutic purposes. These cloned disease-specific antigens are robotically spotted onto protein microarrays and interrogated with serum from the subjects under analyses. These arrays deliver personalized profiles of antigenic exposures and therapeutic targets for personalized immunotherapy. The immune system is the ultimate biosensor, superior to anything a human could create and ready to be exploited for biotechnology and biomedicine." @default.
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• W2030405113 date "2006-12-01" @default.
• W2030405113 modified "2023-10-12" @default.
• W2030405113 title "Epitomics: Global Profiling of Immune Response to Disease Using Protein Microarrays" @default.
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• W2030405113 doi "https://doi.org/10.1089/omi.2006.10.499" @default.
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