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- W2030427706 abstract "A number of studies have shown a positive relationship between diets rich in soluble dietary fibres (SDF) such as β-glucan, pectin, guar gum and psyllium, and reduced serum cholesterol and thus a decreased risk of cardiovascular disease (CVD). Three major biological mechanisms have been proposed to explain the cholesterol-reducing effects of SDF: prevention of bile salt (BS) re-absorption from the small intestine leading to an excess faecal BS excretion; reduced glycemic response leading to lower insulin stimulation of hepatic cholesterol synthesis; and physiological effects of fermentation products of SDF, mainly propionate. Evidence for the latter mechanism is inconclusive, whereas in vivo, ex vivo and in vitro experiments suggest that BS micelles “bind” to SDF preventing their re-absorption. Whereas, glycemic responses to SDF have been studied extensively, the nature of interactions between bile salt micelles and SDF that lead to incomplete BS re-absorption are poorly defined. Three potential physicochemical mechanisms are proposed together with suggestions for in vitro experiments to test them." @default.
- W2030427706 created "2016-06-24" @default.
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- W2030427706 date "2010-01-01" @default.
- W2030427706 modified "2023-10-11" @default.
- W2030427706 title "Mechanisms underlying the cholesterol-lowering properties of soluble dietary fibre polysaccharides" @default.
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- W2030427706 cites W1596984217 @default.
- W2030427706 cites W1754997001 @default.
- W2030427706 cites W1811610985 @default.
- W2030427706 cites W1817501081 @default.
- W2030427706 cites W1835824024 @default.
- W2030427706 cites W1845821296 @default.
- W2030427706 cites W1889642217 @default.
- W2030427706 cites W1895641206 @default.
- W2030427706 cites W1911484843 @default.
- W2030427706 cites W1914396893 @default.
- W2030427706 cites W1955797190 @default.
- W2030427706 cites W1957802592 @default.
- W2030427706 cites W1967684902 @default.
- W2030427706 cites W1969246755 @default.
- W2030427706 cites W1969895628 @default.
- W2030427706 cites W1982246346 @default.
- W2030427706 cites W1992252061 @default.
- W2030427706 cites W1992453415 @default.
- W2030427706 cites W1996041024 @default.
- W2030427706 cites W1997079360 @default.
- W2030427706 cites W2006563939 @default.
- W2030427706 cites W2015539246 @default.
- W2030427706 cites W2020916024 @default.
- W2030427706 cites W2031414151 @default.
- W2030427706 cites W2037693744 @default.
- W2030427706 cites W2039168931 @default.
- W2030427706 cites W2043326717 @default.
- W2030427706 cites W2043551520 @default.
- W2030427706 cites W2044300334 @default.
- W2030427706 cites W2046174595 @default.
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- W2030427706 cites W2113411413 @default.
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- W2030427706 doi "https://doi.org/10.1039/c0fo00080a" @default.
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