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- W2030432861 abstract "<h3>To the Editor.</h3> —We do not share the conclusion of the authors of the DISC study<sup>1</sup>that the results indicate that children who<i>require</i>dietary change to lower their LDL-C levels may<i>safely</i>and<i>successfully</i>do so under supervision (emphasis added). First, although the DISC found no adverse effects on growth, blood chemistry, or psychosocial health, it is not possible, with a 3-year study of only about 300 children per group, to say that the intervention is safe. Although the diet clearly is not grossly hazardous, the real issue is whether there are uncommon, delayed, or subtle harmful effects that exceed the benefits. Given the small magnitude of the benefits, this question remains unanswered. Harms could be far greater than benefits and could still not be found in this study. Second, we disagree that the change of 0.08 mmol/L (3.23 mg/dL) in LDL-C achieved with intensive diet treatment (compared" @default.
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- W2030432861 date "1995-11-08" @default.
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- W2030432861 title "Reducing Dietary Intake of Fat and Cholesterol in Children" @default.
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- W2030432861 doi "https://doi.org/10.1001/jama.1995.03530180017011" @default.
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