FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2030434062> ?p ?o ?g. }

• W2030434062 endingPage "705" @default.
• W2030434062 startingPage "704" @default.
• W2030434062 abstract "Allergic symptoms to a variety of nonstinging insects have been reported.1Wahl R Fraedrich J Occupational allergy to the housefly (Musca domestica).Allergy. 1997; 52: 236-238Crossref PubMed Scopus (17) Google Scholar, 2Soparkar GR Patel PC Cockcroft DW Inhalant atopic sensitivity to grasshoppers in research laboratories.J Allergy Clin Immunol. 1993; 92: 61-65Abstract Full Text PDF PubMed Scopus (15) Google Scholar, 3Siracusa A Bettini P Bacoccoli R Severini C Verga A Abbritti G Asthma caused by live fish bait.J Allergy Clin Immunol. 1994; 93: 424-430Abstract Full Text PDF PubMed Scopus (43) Google Scholar, 4Eriksson NE Ryden B Jonsson P Hypersensitivity to larvae of chironomids (non-biting midges): cross-sensitization with crustaceans.Allergy. 1989; 44: 305-313Crossref PubMed Scopus (49) Google Scholar Many of these are related to occupational exposure in bait shops or research laboratories or to recreational exposure. We are unaware of any previous reports of lady bug sensitivity. A 48-year-old white man with no history of hay fever or asthma or family history of atopy was seen with a 4 months’ duration of nasal and ocular pruritus and sneezing. Symptoms were present at home and work and were not significantly improved by antihistamines, ocular cromolyn, and topical nasal steroid sprays. Physical examination revealed normal-appearing nasal mucosa and watery rhinorrhea. Skin prick testing (SPT) to common commercially available inhalants was nonreactive with a reactive histamine control. Further questioning revealed that his house had been infested with lady bugs for the same amount of time that he been having symptoms. The lady bugs were collected and identified by an expert entomologist (Dr Beverly Sparks, University of Georgia) as Harmonia axyridis. A crude extract was prepared by washing lady bugs from the patient’s home with use of PBS. The lady bugs were then crushed in the saline solution and a 1:10 dilution of the supernatant was used for skin testing. SPT with the lady bug extract produced a 4 × 4 mm wheal with a 20 × 20 mm flare. Two control individuals had no measurable reaction to the lady bug extract but had normal histamine prick responses. A 56-year-old woman was initially evaluated in March 1994 for possible allergic rhinitis. The SPT was positive for trees and negative for other common inhalants. The patient responded to immunotherapy until early 1998, when she again noted upper respiratory symptoms. Repeat SPT was negative to common inhalants, including trees, with appropriately positive and negative controls. A 2-month trial of a steroid nasal spray and an antihistamine resulted in no noticeable improvement. The patient then mentioned that her symptoms correlated with severe episodic lady bug infestations. Lady bugs obtained from the patient’s home were identified by an expert entomologist (Dr Charles Curry, Virginia Tech) as the Asian lady bug, H axyridis. SPT with a lady bug extract prepared as above produced an 11-mm wheal without surrounding erythema. Two control individuals had no measurable reaction to the lady bug extract but had normal histamine responses. To identify proteins in the extract, SDS-PAGE was performed with 15% gels under reducing and nonreducing conditions with Coomassie blue staining. IgE immunoblotting was performed to identify potential allergens. Gels were transferred to nitrocellulose and blocked with TRIS-buffered saline solution–0.5% Tween-20. Nitrocellulose strips were incubated with serum from the patients and 2 controls, washed, and incubated with horseradish peroxidase–labeled antihuman IgE (Biosource International, Camarillo, Calif). After washing, blots were developed by incubation with a chemiluminescence reagent (NEN Life Sciences, Boston, Mass) and recorded by autoradiography. An intensely stained single band was found at 16.6 kd in the first patient but not in the 2 controls. A 16.6-kd band was also revealed in the second patient’s serum, as was an intensely stained 30-kd band that was not observed in the first patient’s serum. No bands were found in the sera of 2 control subjects (Fig 1). Patient 1 used general cleaning methods with good results to remove the lady bugs from his home. His symptoms showed progressive improvement. Eradication of the lady bugs from the home of patient 2 resulted in complete symptomatic improvement. Although inhalant allergy to insects is well known, we are not aware of prior reports of allergic rhinoconjunctivitis to H axyridis. The Asian lady bug was introduced into the southeastern United States in the late 1970s as part of a program to use biologic agents to control aphids that were plaguing farmers and gardeners alike. Unlike the domestic variety, the Asian lady bug is active throughout the year and winters in protected areas, including inside households. The attic is a common portal of entry, but the insects are small enough to enter breaks in the environmental seal of a house. Once inside, they can be eliminated with vigorous environmental measures. Vacuuming, dusting, and adding physical barriers to prevent re-entry should all be used. Caulking gaps and holes and improving the energy seal of the house is a necessity. Dead lady bugs attract pests such as carpet beetles, so insecticides should be avoided. Although certainly impractical, some experts advise moving to lower ground or painting houses black because in their native habitat these beetles winter in the crevices of light-colored cliffs. The true prevalence of lady bug sensitization is not known but may be substantial because lady bug infestation of southeastern homes is common in the winter. Lady bug allergy may be the explanation for some cases of allergic symptoms that have previously eluded diagnosis." @default.
• W2030434062 created "2016-06-24" @default.
• W2030434062 creator A5023469829 @default.
• W2030434062 creator A5044443919 @default.
• W2030434062 creator A5047296309 @default.
• W2030434062 creator A5053926648 @default.
• W2030434062 creator A5082665928 @default.
• W2030434062 creator A5086812749 @default.
• W2030434062 date "1999-09-01" @default.
• W2030434062 modified "2023-10-14" @default.
• W2030434062 title "Allergic rhinoconjunctivitis caused by Harmonia axyridis (Asian lady beetle, Japanese lady beetle, or lady bug)" @default.
• W2030434062 cites W1824527785 @default.
• W2030434062 cites W1983730093 @default.
• W2030434062 cites W2022205422 @default.
• W2030434062 cites W2059330013 @default.
• W2030434062 doi "https://doi.org/10.1016/s0091-6749(99)70347-7" @default.
• W2030434062 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/10482851" @default.
• W2030434062 hasPublicationYear "1999" @default.
• W2030434062 type Work @default.
• W2030434062 sameAs 2030434062 @default.
• W2030434062 citedByCount "52" @default.
• W2030434062 countsByYear W20304340622012 @default.
• W2030434062 countsByYear W20304340622015 @default.
• W2030434062 countsByYear W20304340622016 @default.
• W2030434062 countsByYear W20304340622018 @default.
• W2030434062 countsByYear W20304340622019 @default.
• W2030434062 countsByYear W20304340622022 @default.
• W2030434062 crossrefType "journal-article" @default.
• W2030434062 hasAuthorship W2030434062A5023469829 @default.
• W2030434062 hasAuthorship W2030434062A5044443919 @default.
• W2030434062 hasAuthorship W2030434062A5047296309 @default.
• W2030434062 hasAuthorship W2030434062A5053926648 @default.
• W2030434062 hasAuthorship W2030434062A5082665928 @default.
• W2030434062 hasAuthorship W2030434062A5086812749 @default.
• W2030434062 hasBestOaLocation W20304340621 @default.
• W2030434062 hasConcept C16005928 @default.
• W2030434062 hasConcept C203014093 @default.
• W2030434062 hasConcept C207480886 @default.
• W2030434062 hasConcept C2776042228 @default.
• W2030434062 hasConcept C2777697326 @default.
• W2030434062 hasConcept C71924100 @default.
• W2030434062 hasConceptScore W2030434062C16005928 @default.
• W2030434062 hasConceptScore W2030434062C203014093 @default.
• W2030434062 hasConceptScore W2030434062C207480886 @default.
• W2030434062 hasConceptScore W2030434062C2776042228 @default.
• W2030434062 hasConceptScore W2030434062C2777697326 @default.
• W2030434062 hasConceptScore W2030434062C71924100 @default.
• W2030434062 hasIssue "3" @default.
• W2030434062 hasLocation W20304340621 @default.
• W2030434062 hasLocation W20304340622 @default.
• W2030434062 hasOpenAccess W2030434062 @default.
• W2030434062 hasPrimaryLocation W20304340621 @default.
• W2030434062 hasRelatedWork W1804822064 @default.
• W2030434062 hasRelatedWork W1964534404 @default.
• W2030434062 hasRelatedWork W2079395447 @default.
• W2030434062 hasRelatedWork W2111765493 @default.
• W2030434062 hasRelatedWork W2125880895 @default.
• W2030434062 hasRelatedWork W2139742322 @default.
• W2030434062 hasRelatedWork W2222888505 @default.
• W2030434062 hasRelatedWork W2300739008 @default.
• W2030434062 hasRelatedWork W4206672243 @default.
• W2030434062 hasRelatedWork W2182512484 @default.
• W2030434062 hasVolume "104" @default.
• W2030434062 isParatext "false" @default.
• W2030434062 isRetracted "false" @default.
• W2030434062 magId "2030434062" @default.
• W2030434062 workType "article" @default.