FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2030452669> ?p ?o ?g. }

• W2030452669 endingPage "8362" @default.
• W2030452669 startingPage "8357" @default.
• W2030452669 abstract "The role of cellular interactions in the mechanism of secondary cone photoreceptor degeneration in inherited retinal degenerations in which the mutation specifically affects rod photoreceptors was studied. We developed an organ culture model of whole retinas from 5-week-old mice carrying the retinal degeneration mutation, which at this age contain few remaining rods and numerous surviving cones cocultured with primary cultures of mixed cells from postnatal day 8 normal-sighted mice (C57BL/6) retinas or retinal explants from normal (C57BL/6) or dystrophic (C3H/He) 5-week-old mice. After 7 days, the numbers of residual cone photoreceptors were quantified after specific peanut lectin or anti-arrestin antibody labeling by using an unbiased stereological approach. Examination of organ cultured retinas revealed significantly greater numbers of surviving cones (15–20%) if cultured in the presence of retinas containing normal rods as compared with controls or cocultures with rod-deprived retinas. These data indicate the existence of a diffusible trophic factor released from retinas containing rod cells and acting on retinas in which only cones are present. Because cones are responsible for high acuity and color vision, such data could have important implications not only for eventual therapeutic approaches to human retinal degenerations but also to define interactions between retinal photoreceptor types." @default.
• W2030452669 created "2016-06-24" @default.
• W2030452669 creator A5004150548 @default.
• W2030452669 creator A5006677651 @default.
• W2030452669 creator A5011042825 @default.
• W2030452669 creator A5030345626 @default.
• W2030452669 creator A5033667193 @default.
• W2030452669 creator A5042502698 @default.
• W2030452669 creator A5075171048 @default.
• W2030452669 creator A5077263714 @default.
• W2030452669 creator A5083982156 @default.
• W2030452669 date "1998-07-07" @default.
• W2030452669 modified "2023-10-16" @default.
• W2030452669 title "Normal retina releases a diffusible factor stimulating cone survival in the retinal degeneration mouse" @default.
• W2030452669 cites W12460925 @default.
• W2030452669 cites W157402821 @default.
• W2030452669 cites W1597900071 @default.
• W2030452669 cites W1605371170 @default.
• W2030452669 cites W175108226 @default.
• W2030452669 cites W1977054577 @default.
• W2030452669 cites W1982348610 @default.
• W2030452669 cites W1990217808 @default.
• W2030452669 cites W1992009563 @default.
• W2030452669 cites W1992183658 @default.
• W2030452669 cites W1993263656 @default.
• W2030452669 cites W1995261715 @default.
• W2030452669 cites W1997772006 @default.
• W2030452669 cites W1999972660 @default.
• W2030452669 cites W2005335651 @default.
• W2030452669 cites W2006888091 @default.
• W2030452669 cites W2015963628 @default.
• W2030452669 cites W2021124272 @default.
• W2030452669 cites W2025299744 @default.
• W2030452669 cites W2046694802 @default.
• W2030452669 cites W2058095641 @default.
• W2030452669 cites W2063148034 @default.
• W2030452669 cites W2064771055 @default.
• W2030452669 cites W2066613733 @default.
• W2030452669 cites W2067072602 @default.
• W2030452669 cites W2069790062 @default.
• W2030452669 cites W2071393571 @default.
• W2030452669 cites W2073023809 @default.
• W2030452669 cites W2078479930 @default.
• W2030452669 cites W2078552693 @default.
• W2030452669 cites W2081998461 @default.
• W2030452669 cites W2082540519 @default.
• W2030452669 cites W2083062636 @default.
• W2030452669 cites W2084560356 @default.
• W2030452669 cites W2086859078 @default.
• W2030452669 cites W2087842808 @default.
• W2030452669 cites W2093669238 @default.
• W2030452669 cites W2105382539 @default.
• W2030452669 cites W2112428928 @default.
• W2030452669 cites W2162650178 @default.
• W2030452669 cites W4249024179 @default.
• W2030452669 cites W77228969 @default.
• W2030452669 doi "https://doi.org/10.1073/pnas.95.14.8357" @default.
• W2030452669 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/20980" @default.
• W2030452669 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/9653191" @default.
• W2030452669 hasPublicationYear "1998" @default.
• W2030452669 type Work @default.
• W2030452669 sameAs 2030452669 @default.
• W2030452669 citedByCount "186" @default.
• W2030452669 countsByYear W20304526692012 @default.
• W2030452669 countsByYear W20304526692013 @default.
• W2030452669 countsByYear W20304526692014 @default.
• W2030452669 countsByYear W20304526692015 @default.
• W2030452669 countsByYear W20304526692016 @default.
• W2030452669 countsByYear W20304526692017 @default.
• W2030452669 countsByYear W20304526692018 @default.
• W2030452669 countsByYear W20304526692019 @default.
• W2030452669 countsByYear W20304526692020 @default.
• W2030452669 countsByYear W20304526692021 @default.
• W2030452669 countsByYear W20304526692022 @default.
• W2030452669 countsByYear W20304526692023 @default.
• W2030452669 crossrefType "journal-article" @default.
• W2030452669 hasAuthorship W2030452669A5004150548 @default.
• W2030452669 hasAuthorship W2030452669A5006677651 @default.
• W2030452669 hasAuthorship W2030452669A5011042825 @default.
• W2030452669 hasAuthorship W2030452669A5030345626 @default.
• W2030452669 hasAuthorship W2030452669A5033667193 @default.
• W2030452669 hasAuthorship W2030452669A5042502698 @default.
• W2030452669 hasAuthorship W2030452669A5075171048 @default.
• W2030452669 hasAuthorship W2030452669A5077263714 @default.
• W2030452669 hasAuthorship W2030452669A5083982156 @default.
• W2030452669 hasBestOaLocation W20304526691 @default.
• W2030452669 hasConcept C105702510 @default.
• W2030452669 hasConcept C118487528 @default.
• W2030452669 hasConcept C142724271 @default.
• W2030452669 hasConcept C169760540 @default.
• W2030452669 hasConcept C2776403814 @default.
• W2030452669 hasConcept C2777093970 @default.
• W2030452669 hasConcept C2779354088 @default.
• W2030452669 hasConcept C2780827179 @default.
• W2030452669 hasConcept C2781040256 @default.
• W2030452669 hasConcept C55493867 @default.
• W2030452669 hasConcept C71924100 @default.
• W2030452669 hasConcept C86803240 @default.

• next