Matches in SemOpenAlex for { <https://semopenalex.org/work/W2030481310> ?p ?o ?g. }
- W2030481310 endingPage "64" @default.
- W2030481310 startingPage "55" @default.
- W2030481310 abstract "Relative preservation of dopaminergic axons in patches and a subcallosal layer was observed in the dorsal, lateral and caudal striatum 4 weeks after intrastriatal injection of 6-hydroxydopamine (6-OHDA), a neurotoxin selective for catecholaminergic neurons. Since calcium binding proteins are reported to provide neuroprotective influence in neurons, differences in the distribution of the calcium binding proteins might be related to the different vulnerabilities of dopaminergic neurons and axons to neurotoxins. To address this possibility, we characterized patches of relatively dense tyrosine hydroxylase-immunoreactive (TH-IR) axons in intrastriatal 6-OHDA lesioned rats, focusing on two calcium binding proteins, calbindin (CB) and calretinin (CR). The patches and subcallosal layer of preserved dopaminergic axons in the striatum of rats lesioned with 6-OHDA contained CR, a 31-kDa calcium-binding protein, but interestingly not CB. Dopaminergic neurons containing CR in the substantia nigra pars compacta (SNpc) were relatively spared compared to those that did not contain CR. Taken together, our data indicate that dopaminergic axons and neurons containing CR in the nigrostriatal pathway are more resistant to 6-OHDA lesion than those that do not contain CR." @default.
- W2030481310 created "2016-06-24" @default.
- W2030481310 creator A5050666140 @default.
- W2030481310 creator A5061005767 @default.
- W2030481310 creator A5067969904 @default.
- W2030481310 date "2000-06-01" @default.
- W2030481310 modified "2023-10-10" @default.
- W2030481310 title "Calretinin-containing axons and neurons are resistant to an intrastriatal 6-hydroxydopamine lesion" @default.
- W2030481310 cites W1527671059 @default.
- W2030481310 cites W1795898662 @default.
- W2030481310 cites W1897965317 @default.
- W2030481310 cites W1960561004 @default.
- W2030481310 cites W1968353095 @default.
- W2030481310 cites W1970846389 @default.
- W2030481310 cites W1974898145 @default.
- W2030481310 cites W1977167220 @default.
- W2030481310 cites W1977776486 @default.
- W2030481310 cites W1983383694 @default.
- W2030481310 cites W1989684326 @default.
- W2030481310 cites W1992587213 @default.
- W2030481310 cites W1992673078 @default.
- W2030481310 cites W2001551525 @default.
- W2030481310 cites W2002343527 @default.
- W2030481310 cites W2003717217 @default.
- W2030481310 cites W2009289169 @default.
- W2030481310 cites W2011226249 @default.
- W2030481310 cites W2026671696 @default.
- W2030481310 cites W2027677864 @default.
- W2030481310 cites W2029717418 @default.
- W2030481310 cites W2032551004 @default.
- W2030481310 cites W2037233527 @default.
- W2030481310 cites W2047685096 @default.
- W2030481310 cites W2048719661 @default.
- W2030481310 cites W2050636568 @default.
- W2030481310 cites W2054319504 @default.
- W2030481310 cites W2057515174 @default.
- W2030481310 cites W2065000444 @default.
- W2030481310 cites W2065601975 @default.
- W2030481310 cites W2073819910 @default.
- W2030481310 cites W2073861433 @default.
- W2030481310 cites W2077951241 @default.
- W2030481310 cites W2088415801 @default.
- W2030481310 cites W2089635976 @default.
- W2030481310 cites W2092957824 @default.
- W2030481310 cites W2112777355 @default.
- W2030481310 cites W2140075873 @default.
- W2030481310 cites W2164158899 @default.
- W2030481310 cites W2220358217 @default.
- W2030481310 cites W2345246347 @default.
- W2030481310 doi "https://doi.org/10.1016/s0006-8993(00)02219-8" @default.
- W2030481310 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/10825480" @default.
- W2030481310 hasPublicationYear "2000" @default.
- W2030481310 type Work @default.
- W2030481310 sameAs 2030481310 @default.
- W2030481310 citedByCount "35" @default.
- W2030481310 countsByYear W20304813102012 @default.
- W2030481310 countsByYear W20304813102013 @default.
- W2030481310 countsByYear W20304813102014 @default.
- W2030481310 countsByYear W20304813102015 @default.
- W2030481310 countsByYear W20304813102016 @default.
- W2030481310 countsByYear W20304813102017 @default.
- W2030481310 countsByYear W20304813102018 @default.
- W2030481310 countsByYear W20304813102020 @default.
- W2030481310 countsByYear W20304813102021 @default.
- W2030481310 countsByYear W20304813102023 @default.
- W2030481310 crossrefType "journal-article" @default.
- W2030481310 hasAuthorship W2030481310A5050666140 @default.
- W2030481310 hasAuthorship W2030481310A5061005767 @default.
- W2030481310 hasAuthorship W2030481310A5067969904 @default.
- W2030481310 hasConcept C122229402 @default.
- W2030481310 hasConcept C126322002 @default.
- W2030481310 hasConcept C134018914 @default.
- W2030481310 hasConcept C137183658 @default.
- W2030481310 hasConcept C159167319 @default.
- W2030481310 hasConcept C169760540 @default.
- W2030481310 hasConcept C203014093 @default.
- W2030481310 hasConcept C204232928 @default.
- W2030481310 hasConcept C26265296 @default.
- W2030481310 hasConcept C2776773494 @default.
- W2030481310 hasConcept C2777288102 @default.
- W2030481310 hasConcept C2780062018 @default.
- W2030481310 hasConcept C2780358027 @default.
- W2030481310 hasConcept C2780938664 @default.
- W2030481310 hasConcept C2781404787 @default.
- W2030481310 hasConcept C2911016594 @default.
- W2030481310 hasConcept C513476851 @default.
- W2030481310 hasConcept C519063684 @default.
- W2030481310 hasConcept C71924100 @default.
- W2030481310 hasConcept C86803240 @default.
- W2030481310 hasConceptScore W2030481310C122229402 @default.
- W2030481310 hasConceptScore W2030481310C126322002 @default.
- W2030481310 hasConceptScore W2030481310C134018914 @default.
- W2030481310 hasConceptScore W2030481310C137183658 @default.
- W2030481310 hasConceptScore W2030481310C159167319 @default.
- W2030481310 hasConceptScore W2030481310C169760540 @default.
- W2030481310 hasConceptScore W2030481310C203014093 @default.
- W2030481310 hasConceptScore W2030481310C204232928 @default.
- W2030481310 hasConceptScore W2030481310C26265296 @default.