Matches in SemOpenAlex for { <https://semopenalex.org/work/W2030499978> ?p ?o ?g. }
Showing items 1 to 94 of
94
with 100 items per page.
- W2030499978 endingPage "174" @default.
- W2030499978 startingPage "169" @default.
- W2030499978 abstract "A novel immunological approach to the problem of the detection and molar evaluation of vasopressin precursors was taken. First, the specificity of anti-vasopressin antibodies was studied and the hormone antigenic determinant was identified as the sequence Cys-Pro-Arg-Gly-NH2. Then this antigenic determinant, not originally shared by the precursors, was reconstituted by tryptic cleavage followed by chemical fixation of glycinamide. This treatment made quantification of precursors by radioimmunoassay possible at a fmol level in various tissues. In normal rat, precursors were found only in the supraoptic nucleus (192 pmol/mg protein), paraventricular nucleus, median eminence and posterior lobe of the hypophysis. The maturation process was followed by the decrease of the ratio of precursor to hormone from 4-5 to 0.02 along the hypothalamo-hypophysial axis. In Brattleboro rats, genetically deficient in vasopressin, no precursor could be detected over the background level; that ensures the specificity and reliability of this approach." @default.
- W2030499978 created "2016-06-24" @default.
- W2030499978 creator A5004340066 @default.
- W2030499978 creator A5024875426 @default.
- W2030499978 creator A5063987135 @default.
- W2030499978 date "2005-03-03" @default.
- W2030499978 modified "2023-09-25" @default.
- W2030499978 title "Inimunochemical Detection of Vasopressin Precursors: Artificial Processing and Quantification along the Hypothalamo-Hypophysial Axis" @default.
- W2030499978 cites W1490409795 @default.
- W2030499978 cites W1576127641 @default.
- W2030499978 cites W1987289944 @default.
- W2030499978 cites W1987743061 @default.
- W2030499978 cites W201648669 @default.
- W2030499978 cites W2023288163 @default.
- W2030499978 cites W2029302518 @default.
- W2030499978 cites W2033785962 @default.
- W2030499978 cites W2037491995 @default.
- W2030499978 cites W2058944682 @default.
- W2030499978 cites W2059537977 @default.
- W2030499978 cites W2074928882 @default.
- W2030499978 cites W2080249486 @default.
- W2030499978 cites W2089562128 @default.
- W2030499978 cites W2090208971 @default.
- W2030499978 cites W2093169206 @default.
- W2030499978 cites W4239456555 @default.
- W2030499978 doi "https://doi.org/10.1111/j.1432-1033.1981.tb06213.x" @default.
- W2030499978 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/6164552" @default.
- W2030499978 hasPublicationYear "2005" @default.
- W2030499978 type Work @default.
- W2030499978 sameAs 2030499978 @default.
- W2030499978 citedByCount "12" @default.
- W2030499978 crossrefType "journal-article" @default.
- W2030499978 hasAuthorship W2030499978A5004340066 @default.
- W2030499978 hasAuthorship W2030499978A5024875426 @default.
- W2030499978 hasAuthorship W2030499978A5063987135 @default.
- W2030499978 hasBestOaLocation W20304999781 @default.
- W2030499978 hasConcept C118303440 @default.
- W2030499978 hasConcept C126322002 @default.
- W2030499978 hasConcept C134018914 @default.
- W2030499978 hasConcept C170493617 @default.
- W2030499978 hasConcept C176685330 @default.
- W2030499978 hasConcept C185592680 @default.
- W2030499978 hasConcept C2776176026 @default.
- W2030499978 hasConcept C2776370428 @default.
- W2030499978 hasConcept C2777003273 @default.
- W2030499978 hasConcept C2777687476 @default.
- W2030499978 hasConcept C2779067335 @default.
- W2030499978 hasConcept C2780723820 @default.
- W2030499978 hasConcept C55493867 @default.
- W2030499978 hasConcept C6162580 @default.
- W2030499978 hasConcept C71315377 @default.
- W2030499978 hasConcept C71924100 @default.
- W2030499978 hasConcept C86803240 @default.
- W2030499978 hasConcept C95444343 @default.
- W2030499978 hasConceptScore W2030499978C118303440 @default.
- W2030499978 hasConceptScore W2030499978C126322002 @default.
- W2030499978 hasConceptScore W2030499978C134018914 @default.
- W2030499978 hasConceptScore W2030499978C170493617 @default.
- W2030499978 hasConceptScore W2030499978C176685330 @default.
- W2030499978 hasConceptScore W2030499978C185592680 @default.
- W2030499978 hasConceptScore W2030499978C2776176026 @default.
- W2030499978 hasConceptScore W2030499978C2776370428 @default.
- W2030499978 hasConceptScore W2030499978C2777003273 @default.
- W2030499978 hasConceptScore W2030499978C2777687476 @default.
- W2030499978 hasConceptScore W2030499978C2779067335 @default.
- W2030499978 hasConceptScore W2030499978C2780723820 @default.
- W2030499978 hasConceptScore W2030499978C55493867 @default.
- W2030499978 hasConceptScore W2030499978C6162580 @default.
- W2030499978 hasConceptScore W2030499978C71315377 @default.
- W2030499978 hasConceptScore W2030499978C71924100 @default.
- W2030499978 hasConceptScore W2030499978C86803240 @default.
- W2030499978 hasConceptScore W2030499978C95444343 @default.
- W2030499978 hasIssue "1" @default.
- W2030499978 hasLocation W20304999781 @default.
- W2030499978 hasLocation W20304999782 @default.
- W2030499978 hasOpenAccess W2030499978 @default.
- W2030499978 hasPrimaryLocation W20304999781 @default.
- W2030499978 hasRelatedWork W1978447652 @default.
- W2030499978 hasRelatedWork W2035925953 @default.
- W2030499978 hasRelatedWork W2073355718 @default.
- W2030499978 hasRelatedWork W2074358091 @default.
- W2030499978 hasRelatedWork W2082377541 @default.
- W2030499978 hasRelatedWork W2082913778 @default.
- W2030499978 hasRelatedWork W2083903426 @default.
- W2030499978 hasRelatedWork W2094511447 @default.
- W2030499978 hasRelatedWork W3172415625 @default.
- W2030499978 hasRelatedWork W4237586391 @default.
- W2030499978 hasVolume "115" @default.
- W2030499978 isParatext "false" @default.
- W2030499978 isRetracted "false" @default.
- W2030499978 magId "2030499978" @default.
- W2030499978 workType "article" @default.