Matches in SemOpenAlex for { <https://semopenalex.org/work/W2030529731> ?p ?o ?g. }
Showing items 1 to 82 of
82
with 100 items per page.
- W2030529731 endingPage "88" @default.
- W2030529731 startingPage "84" @default.
- W2030529731 abstract "Continuous interscalene brachial plexus block with a single dose of 0.5% bupivacaine 1.25 mg/kg, continued with an infusion of 0.25% bupivacaine 0.25 mg/kg/h, was performed on 24 patients to provide analgesia during shoulder surgery and in the postoperative period. The drugs for general anaesthesia included glycopyrrolate, thiopentone, vecuronium, enflurane and N2O/O2. All patients had signs of regional analgesia 30 min after the block without haemodynamic problems. The infusion of local anaesthetic was interrupted in six patients because of a failure in catheter function. Of the remaining 18 patients, nine needed no complementary analgesics and nine patients received, on average, 1.6 doses of oxycodone (0.15 mg/kg/dose) during a 24-h period. Displacement of the interscalene catheters could be prevented by a fixation suture to the skin. Two patients noted a metallic taste during the bupivacaine infusion. The most common complaints were numbness of the hand (n = 15) and hoarseness (n = 5). The mean (+/- s.e.mean) plasma concentrations of bupivacaine at 30, 60, 180 min and 24 h were 0.68 +/- 0.06, 0.62 +/- 0.05, 0.52 +/- 0.04 and 0.76 +/- 0.01 micrograms/ml, respectively. During the 24-h period, the alpha 1-acid glycoprotein (AAG) concentration (mean +/- s.e.mean) in plasma rose from 0.41 +/- 0.04 g/l to 0.54 +/- 0.04 g/l (P less than 0.001). The concentration of free bupivacaine was below detectable levels (less than 0.01 micrograms/ml) after the 24-h infusion. The rise in AAG probably increases binding of bupivacaine to plasma proteins, diminishing the risk of systemic toxicity." @default.
- W2030529731 created "2016-06-24" @default.
- W2030529731 creator A5052836829 @default.
- W2030529731 creator A5078005733 @default.
- W2030529731 creator A5088980841 @default.
- W2030529731 creator A5090906424 @default.
- W2030529731 date "1989-01-01" @default.
- W2030529731 modified "2023-10-16" @default.
- W2030529731 title "Continuous interscalene brachial plexus block: clinical efficacy, technical problems and bupivacaine plasma concentrations" @default.
- W2030529731 cites W1984521462 @default.
- W2030529731 cites W1986457340 @default.
- W2030529731 cites W1986778625 @default.
- W2030529731 cites W2004140403 @default.
- W2030529731 cites W2023833111 @default.
- W2030529731 cites W2032988573 @default.
- W2030529731 cites W2039008967 @default.
- W2030529731 cites W2083175211 @default.
- W2030529731 cites W2094416355 @default.
- W2030529731 cites W2098381491 @default.
- W2030529731 cites W2149463631 @default.
- W2030529731 doi "https://doi.org/10.1111/j.1399-6576.1989.tb02866.x" @default.
- W2030529731 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/2916392" @default.
- W2030529731 hasPublicationYear "1989" @default.
- W2030529731 type Work @default.
- W2030529731 sameAs 2030529731 @default.
- W2030529731 citedByCount "88" @default.
- W2030529731 countsByYear W20305297312012 @default.
- W2030529731 countsByYear W20305297312013 @default.
- W2030529731 countsByYear W20305297312014 @default.
- W2030529731 countsByYear W20305297312017 @default.
- W2030529731 countsByYear W20305297312019 @default.
- W2030529731 countsByYear W20305297312020 @default.
- W2030529731 countsByYear W20305297312021 @default.
- W2030529731 crossrefType "journal-article" @default.
- W2030529731 hasAuthorship W2030529731A5052836829 @default.
- W2030529731 hasAuthorship W2030529731A5078005733 @default.
- W2030529731 hasAuthorship W2030529731A5088980841 @default.
- W2030529731 hasAuthorship W2030529731A5090906424 @default.
- W2030529731 hasConcept C141071460 @default.
- W2030529731 hasConcept C2776572635 @default.
- W2030529731 hasConcept C2777876916 @default.
- W2030529731 hasConcept C2778994108 @default.
- W2030529731 hasConcept C2780149897 @default.
- W2030529731 hasConcept C2781151446 @default.
- W2030529731 hasConcept C2781267111 @default.
- W2030529731 hasConcept C2781328992 @default.
- W2030529731 hasConcept C3018112808 @default.
- W2030529731 hasConcept C42219234 @default.
- W2030529731 hasConcept C71924100 @default.
- W2030529731 hasConceptScore W2030529731C141071460 @default.
- W2030529731 hasConceptScore W2030529731C2776572635 @default.
- W2030529731 hasConceptScore W2030529731C2777876916 @default.
- W2030529731 hasConceptScore W2030529731C2778994108 @default.
- W2030529731 hasConceptScore W2030529731C2780149897 @default.
- W2030529731 hasConceptScore W2030529731C2781151446 @default.
- W2030529731 hasConceptScore W2030529731C2781267111 @default.
- W2030529731 hasConceptScore W2030529731C2781328992 @default.
- W2030529731 hasConceptScore W2030529731C3018112808 @default.
- W2030529731 hasConceptScore W2030529731C42219234 @default.
- W2030529731 hasConceptScore W2030529731C71924100 @default.
- W2030529731 hasIssue "1" @default.
- W2030529731 hasLocation W20305297311 @default.
- W2030529731 hasLocation W20305297312 @default.
- W2030529731 hasOpenAccess W2030529731 @default.
- W2030529731 hasPrimaryLocation W20305297311 @default.
- W2030529731 hasRelatedWork W2083835538 @default.
- W2030529731 hasRelatedWork W2376938339 @default.
- W2030529731 hasRelatedWork W2378343060 @default.
- W2030529731 hasRelatedWork W2393236800 @default.
- W2030529731 hasRelatedWork W2420474403 @default.
- W2030529731 hasRelatedWork W2559920336 @default.
- W2030529731 hasRelatedWork W2615614638 @default.
- W2030529731 hasRelatedWork W3081663094 @default.
- W2030529731 hasRelatedWork W3193884938 @default.
- W2030529731 hasRelatedWork W4320025834 @default.
- W2030529731 hasVolume "33" @default.
- W2030529731 isParatext "false" @default.
- W2030529731 isRetracted "false" @default.
- W2030529731 magId "2030529731" @default.
- W2030529731 workType "article" @default.