FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2030550786> ?p ?o ?g. }

• W2030550786 endingPage "1835" @default.
• W2030550786 startingPage "1828" @default.
• W2030550786 abstract "There is a great need to design better orthopaedic implant devices by modifying their surface properties. In this respect, one approach that has received much attention of late is the simulation of the surface roughness of bone in synthetic orthopaedic implant materials. Bone has numerous nanometre features due to the presence of nanostructured entities such as collagen and hydroxyapatite. Despite this fact, current orthopaedic implant materials are smooth at the nanoscale. Previous studies have measured increased osteoblast (bone-forming cell) functions on biologically inspired nanophase titania compared to conventional titania formulations. In fact, in vitro calcium deposition by osteoblasts was up to three times higher on nanostructured compared to conventional titania. However, it was unclear in those studies what underlying surface properties (roughness, crystallinity, crystal phase, chemistry, etc) promoted enhanced functions of osteoblasts on nanophase titania. For that reason, the objective of the present in vitro study was to specifically determine the role nanostructured surface roughness of titania had on increasing functions of osteoblasts. To achieve this, the surface roughness of nanophase and conventional titania was transferred to a model tissue engineering polymer: poly-lactic-co-glycolic acid (PLGA). Results of the present study demonstrated greater osteoblast adhesion and proliferation for up to 5 days of culture on PLGA moulds of nanophase compared to conventional titania. In this manner, this study elucidated that the property of nanophase titania which increased osteoblast function was a large degree of nanometre surface features that mimicked bone. For this reason, nanophase materials deserve more attention in improving orthopaedic implant applications." @default.
• W2030550786 created "2016-06-24" @default.
• W2030550786 creator A5002555668 @default.
• W2030550786 creator A5033703845 @default.
• W2030550786 creator A5076201188 @default.
• W2030550786 date "2005-07-18" @default.
• W2030550786 modified "2023-10-08" @default.
• W2030550786 title "Mimicking the nanofeatures of bone increases bone-forming cell adhesion and proliferation" @default.
• W2030550786 cites W1987969362 @default.
• W2030550786 cites W2000100674 @default.
• W2030550786 cites W2002678826 @default.
• W2030550786 cites W2012293496 @default.
• W2030550786 cites W2014023656 @default.
• W2030550786 cites W2019520860 @default.
• W2030550786 cites W2024312520 @default.
• W2030550786 cites W2031395064 @default.
• W2030550786 cites W2031876019 @default.
• W2030550786 cites W2044062630 @default.
• W2030550786 cites W2045383620 @default.
• W2030550786 cites W2052974206 @default.
• W2030550786 cites W2065749233 @default.
• W2030550786 cites W2080167589 @default.
• W2030550786 cites W2084154538 @default.
• W2030550786 cites W2093883262 @default.
• W2030550786 cites W2094298128 @default.
• W2030550786 cites W2096005599 @default.
• W2030550786 cites W2119933023 @default.
• W2030550786 cites W2984921322 @default.
• W2030550786 doi "https://doi.org/10.1088/0957-4484/16/9/069" @default.
• W2030550786 hasPublicationYear "2005" @default.
• W2030550786 type Work @default.
• W2030550786 sameAs 2030550786 @default.
• W2030550786 citedByCount "194" @default.
• W2030550786 countsByYear W20305507862012 @default.
• W2030550786 countsByYear W20305507862013 @default.
• W2030550786 countsByYear W20305507862014 @default.
• W2030550786 countsByYear W20305507862015 @default.
• W2030550786 countsByYear W20305507862016 @default.
• W2030550786 countsByYear W20305507862017 @default.
• W2030550786 countsByYear W20305507862018 @default.
• W2030550786 countsByYear W20305507862019 @default.
• W2030550786 countsByYear W20305507862020 @default.
• W2030550786 countsByYear W20305507862021 @default.
• W2030550786 countsByYear W20305507862022 @default.
• W2030550786 countsByYear W20305507862023 @default.
• W2030550786 crossrefType "journal-article" @default.
• W2030550786 hasAuthorship W2030550786A5002555668 @default.
• W2030550786 hasAuthorship W2030550786A5033703845 @default.
• W2030550786 hasAuthorship W2030550786A5076201188 @default.
• W2030550786 hasConcept C101414908 @default.
• W2030550786 hasConcept C107365816 @default.
• W2030550786 hasConcept C136229726 @default.
• W2030550786 hasConcept C141071460 @default.
• W2030550786 hasConcept C155672457 @default.
• W2030550786 hasConcept C159985019 @default.
• W2030550786 hasConcept C171250308 @default.
• W2030550786 hasConcept C185592680 @default.
• W2030550786 hasConcept C192562407 @default.
• W2030550786 hasConcept C202751555 @default.
• W2030550786 hasConcept C2777803738 @default.
• W2030550786 hasConcept C2778260815 @default.
• W2030550786 hasConcept C2780165375 @default.
• W2030550786 hasConcept C2781411149 @default.
• W2030550786 hasConcept C45206210 @default.
• W2030550786 hasConcept C46275449 @default.
• W2030550786 hasConcept C55493867 @default.
• W2030550786 hasConcept C71039073 @default.
• W2030550786 hasConcept C71924100 @default.
• W2030550786 hasConcept C77066764 @default.
• W2030550786 hasConcept C84416704 @default.
• W2030550786 hasConcept C85789140 @default.
• W2030550786 hasConceptScore W2030550786C101414908 @default.
• W2030550786 hasConceptScore W2030550786C107365816 @default.
• W2030550786 hasConceptScore W2030550786C136229726 @default.
• W2030550786 hasConceptScore W2030550786C141071460 @default.
• W2030550786 hasConceptScore W2030550786C155672457 @default.
• W2030550786 hasConceptScore W2030550786C159985019 @default.
• W2030550786 hasConceptScore W2030550786C171250308 @default.
• W2030550786 hasConceptScore W2030550786C185592680 @default.
• W2030550786 hasConceptScore W2030550786C192562407 @default.
• W2030550786 hasConceptScore W2030550786C202751555 @default.
• W2030550786 hasConceptScore W2030550786C2777803738 @default.
• W2030550786 hasConceptScore W2030550786C2778260815 @default.
• W2030550786 hasConceptScore W2030550786C2780165375 @default.
• W2030550786 hasConceptScore W2030550786C2781411149 @default.
• W2030550786 hasConceptScore W2030550786C45206210 @default.
• W2030550786 hasConceptScore W2030550786C46275449 @default.
• W2030550786 hasConceptScore W2030550786C55493867 @default.
• W2030550786 hasConceptScore W2030550786C71039073 @default.
• W2030550786 hasConceptScore W2030550786C71924100 @default.
• W2030550786 hasConceptScore W2030550786C77066764 @default.
• W2030550786 hasConceptScore W2030550786C84416704 @default.
• W2030550786 hasConceptScore W2030550786C85789140 @default.
• W2030550786 hasIssue "9" @default.
• W2030550786 hasLocation W20305507861 @default.
• W2030550786 hasOpenAccess W2030550786 @default.
• W2030550786 hasPrimaryLocation W20305507861 @default.
• W2030550786 hasRelatedWork W1968240876 @default.

• next