Matches in SemOpenAlex for { <https://semopenalex.org/work/W2030555280> ?p ?o ?g. }
- W2030555280 endingPage "99" @default.
- W2030555280 startingPage "85" @default.
- W2030555280 abstract "A slow-growing, aminoglycoside-resistant mutant and a rapidly-growing psuedorevertant were isolated from Aeromonas salmonicida, the causative agent of salmonid furunculosis. These mutants continued to elicit a variety of classical virulence factors associated with A. salmonicida pathogenesis. They differed morphologically from the wild-type and from one another with respect to A-layer organization, membrane antagonist sensitivity and particularly to aerobic metabolism. Both mutants were drastically altered in the architecture of the 2D crystalline surface array (A-layer), although both were similar to wild-type with respect to cell surface composition. The slow-growing, antibiotic-resistant mutant differed significantly from the wildtype by the apparent loss of virtually all aerobic metabolism; the pseudorevertant had partially recovered the ability to aerobically metabolize certain carbon sources. Both mutants were avirulent and incapable of tissue persistence. The rapidly-growing, antibiotic-sensitive pseudorevertant, when administered either intraperitoneally or by immersion, effectively protected salmonid fish from challenge by a heterologous virulent strain suggesting its candidature as a live, attenuated furunculosis vaccine." @default.
- W2030555280 created "2016-06-24" @default.
- W2030555280 creator A5009720118 @default.
- W2030555280 creator A5033376363 @default.
- W2030555280 creator A5038097646 @default.
- W2030555280 creator A5061273048 @default.
- W2030555280 date "1991-08-01" @default.
- W2030555280 modified "2023-10-10" @default.
- W2030555280 title "Surface-disorganized, attenuated mutants of Aeromonas salmonicida as furunculosis live vaccines" @default.
- W2030555280 cites W1502286385 @default.
- W2030555280 cites W1529512777 @default.
- W2030555280 cites W1531941910 @default.
- W2030555280 cites W1538255618 @default.
- W2030555280 cites W1646879892 @default.
- W2030555280 cites W1743645902 @default.
- W2030555280 cites W1777261165 @default.
- W2030555280 cites W1808469215 @default.
- W2030555280 cites W1817723632 @default.
- W2030555280 cites W1831066112 @default.
- W2030555280 cites W1878324752 @default.
- W2030555280 cites W1943943023 @default.
- W2030555280 cites W1985782125 @default.
- W2030555280 cites W2000381613 @default.
- W2030555280 cites W2013740990 @default.
- W2030555280 cites W2027496803 @default.
- W2030555280 cites W2031423487 @default.
- W2030555280 cites W2039089717 @default.
- W2030555280 cites W2042048278 @default.
- W2030555280 cites W2043880676 @default.
- W2030555280 cites W2049371128 @default.
- W2030555280 cites W2054328951 @default.
- W2030555280 cites W2066577501 @default.
- W2030555280 cites W2068945982 @default.
- W2030555280 cites W2076922976 @default.
- W2030555280 cites W2091700899 @default.
- W2030555280 cites W2094570176 @default.
- W2030555280 cites W2097243058 @default.
- W2030555280 cites W2133050254 @default.
- W2030555280 cites W2139525000 @default.
- W2030555280 cites W2140820244 @default.
- W2030555280 cites W2153558803 @default.
- W2030555280 cites W2160914020 @default.
- W2030555280 cites W2169912440 @default.
- W2030555280 cites W2329145054 @default.
- W2030555280 cites W2624205100 @default.
- W2030555280 doi "https://doi.org/10.1016/0882-4010(91)90002-r" @default.
- W2030555280 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/1961112" @default.
- W2030555280 hasPublicationYear "1991" @default.
- W2030555280 type Work @default.
- W2030555280 sameAs 2030555280 @default.
- W2030555280 citedByCount "44" @default.
- W2030555280 countsByYear W20305552802012 @default.
- W2030555280 countsByYear W20305552802016 @default.
- W2030555280 countsByYear W20305552802019 @default.
- W2030555280 countsByYear W20305552802020 @default.
- W2030555280 countsByYear W20305552802022 @default.
- W2030555280 countsByYear W20305552802023 @default.
- W2030555280 crossrefType "journal-article" @default.
- W2030555280 hasAuthorship W2030555280A5009720118 @default.
- W2030555280 hasAuthorship W2030555280A5033376363 @default.
- W2030555280 hasAuthorship W2030555280A5038097646 @default.
- W2030555280 hasAuthorship W2030555280A5061273048 @default.
- W2030555280 hasConcept C104317684 @default.
- W2030555280 hasConcept C143065580 @default.
- W2030555280 hasConcept C207583985 @default.
- W2030555280 hasConcept C2779729001 @default.
- W2030555280 hasConcept C2780115692 @default.
- W2030555280 hasConcept C523546767 @default.
- W2030555280 hasConcept C54355233 @default.
- W2030555280 hasConcept C54602769 @default.
- W2030555280 hasConcept C60987743 @default.
- W2030555280 hasConcept C86803240 @default.
- W2030555280 hasConcept C89423630 @default.
- W2030555280 hasConceptScore W2030555280C104317684 @default.
- W2030555280 hasConceptScore W2030555280C143065580 @default.
- W2030555280 hasConceptScore W2030555280C207583985 @default.
- W2030555280 hasConceptScore W2030555280C2779729001 @default.
- W2030555280 hasConceptScore W2030555280C2780115692 @default.
- W2030555280 hasConceptScore W2030555280C523546767 @default.
- W2030555280 hasConceptScore W2030555280C54355233 @default.
- W2030555280 hasConceptScore W2030555280C54602769 @default.
- W2030555280 hasConceptScore W2030555280C60987743 @default.
- W2030555280 hasConceptScore W2030555280C86803240 @default.
- W2030555280 hasConceptScore W2030555280C89423630 @default.
- W2030555280 hasIssue "2" @default.
- W2030555280 hasLocation W20305552801 @default.
- W2030555280 hasLocation W20305552802 @default.
- W2030555280 hasOpenAccess W2030555280 @default.
- W2030555280 hasPrimaryLocation W20305552801 @default.
- W2030555280 hasRelatedWork W2034214034 @default.
- W2030555280 hasRelatedWork W2050122265 @default.
- W2030555280 hasRelatedWork W2067158236 @default.
- W2030555280 hasRelatedWork W2114009169 @default.
- W2030555280 hasRelatedWork W2149425604 @default.
- W2030555280 hasRelatedWork W2153133457 @default.
- W2030555280 hasRelatedWork W2166672798 @default.
- W2030555280 hasRelatedWork W2564367133 @default.
- W2030555280 hasRelatedWork W2765588319 @default.