FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2030571880> ?p ?o ?g. }

• W2030571880 endingPage "1347" @default.
• W2030571880 startingPage "1342" @default.
• W2030571880 abstract "The endogenous ligand for the growth hormone (GH) secretagogue receptor ghrelin is a peptide secreted by the stomach of mammals and stimulates food intake and enhances adiposity. In avian species, ghrelin is mainly produced by the proventriculus but reduces food intake whereas its effect on lipogenesis in different tissues is unknown. We therefore investigated the effects of a single intravenous injection of 2.8 μg (1 nmol per chick) recombinant chicken ghrelin in neonatal broiler chicks. Besides food intake and plasma corticosterone levels, mRNA levels of the key lipogenic enzyme fatty acid synthase (FAS) and its related transcription factors sterol regulatory element binding protein-1 (SREBP-1) and peroxisome proliferator-activated receptor-γ (PPARγ) were determined in diencephalon, liver and quadriceps femoris muscle before, and 15, 30, and 60 min after injection. Chicken ghrelin administration induced a significant short-term (<30 min) reduction in food intake and markedly elevated plasma corticosterone levels. In diencephalon, FAS, SREBP-1 and PPARγ mRNA levels were significantly increased within 15 min after ghrelin injection. These observations suggest that central fatty acid metabolism is involved in the anorectic effects of ghrelin. In contrast, hepatic mRNA levels of FAS and both transcription factors were significantly reduced within 30 min after ghrelin injection. In muscle, FAS and transcription factor gene expression was very low and not affected by ghrelin. Overall, our results indicate that ghrelin has opposite effects on FAS and transcription factor mRNA amounts with increased levels in diencephalon (central anorectic effect) and decreased levels in liver (peripheral anti-lipogenic effect) in chickens." @default.
• W2030571880 created "2016-06-24" @default.
• W2030571880 creator A5016359634 @default.
• W2030571880 creator A5016844196 @default.
• W2030571880 creator A5020720210 @default.
• W2030571880 creator A5021693858 @default.
• W2030571880 creator A5048475867 @default.
• W2030571880 creator A5071474327 @default.
• W2030571880 creator A5072432961 @default.
• W2030571880 date "2009-07-01" @default.
• W2030571880 modified "2023-10-18" @default.
• W2030571880 title "Ghrelin modulates fatty acid synthase and related transcription factor mRNA levels in a tissue-specific manner in neonatal broiler chicks" @default.
• W2030571880 cites W1637971961 @default.
• W2030571880 cites W1964750158 @default.
• W2030571880 cites W1975344770 @default.
• W2030571880 cites W2009427770 @default.
• W2030571880 cites W2014946315 @default.
• W2030571880 cites W2020843850 @default.
• W2030571880 cites W2028398575 @default.
• W2030571880 cites W2041170339 @default.
• W2030571880 cites W2050192492 @default.
• W2030571880 cites W2057712755 @default.
• W2030571880 cites W2067333453 @default.
• W2030571880 cites W2072322276 @default.
• W2030571880 cites W2077982572 @default.
• W2030571880 cites W2081318765 @default.
• W2030571880 cites W2089884502 @default.
• W2030571880 cites W2098545392 @default.
• W2030571880 cites W2102521284 @default.
• W2030571880 cites W2125745486 @default.
• W2030571880 cites W2127017433 @default.
• W2030571880 cites W2128533132 @default.
• W2030571880 cites W2129528230 @default.
• W2030571880 cites W2132286258 @default.
• W2030571880 cites W2133620886 @default.
• W2030571880 cites W2152261846 @default.
• W2030571880 cites W2160617522 @default.
• W2030571880 cites W2163865122 @default.
• W2030571880 doi "https://doi.org/10.1016/j.peptides.2009.04.015" @default.
• W2030571880 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/19409434" @default.
• W2030571880 hasPublicationYear "2009" @default.
• W2030571880 type Work @default.
• W2030571880 sameAs 2030571880 @default.
• W2030571880 citedByCount "47" @default.
• W2030571880 countsByYear W20305718802012 @default.
• W2030571880 countsByYear W20305718802013 @default.
• W2030571880 countsByYear W20305718802014 @default.
• W2030571880 countsByYear W20305718802015 @default.
• W2030571880 countsByYear W20305718802016 @default.
• W2030571880 countsByYear W20305718802017 @default.
• W2030571880 countsByYear W20305718802018 @default.
• W2030571880 countsByYear W20305718802019 @default.
• W2030571880 countsByYear W20305718802020 @default.
• W2030571880 countsByYear W20305718802022 @default.
• W2030571880 countsByYear W20305718802023 @default.
• W2030571880 crossrefType "journal-article" @default.
• W2030571880 hasAuthorship W2030571880A5016359634 @default.
• W2030571880 hasAuthorship W2030571880A5016844196 @default.
• W2030571880 hasAuthorship W2030571880A5020720210 @default.
• W2030571880 hasAuthorship W2030571880A5021693858 @default.
• W2030571880 hasAuthorship W2030571880A5048475867 @default.
• W2030571880 hasAuthorship W2030571880A5071474327 @default.
• W2030571880 hasAuthorship W2030571880A5072432961 @default.
• W2030571880 hasConcept C126322002 @default.
• W2030571880 hasConcept C134018914 @default.
• W2030571880 hasConcept C141359234 @default.
• W2030571880 hasConcept C170493617 @default.
• W2030571880 hasConcept C185592680 @default.
• W2030571880 hasConcept C2777369949 @default.
• W2030571880 hasConcept C2779357093 @default.
• W2030571880 hasConcept C2780352252 @default.
• W2030571880 hasConcept C3018685816 @default.
• W2030571880 hasConcept C4733338 @default.
• W2030571880 hasConcept C48289651 @default.
• W2030571880 hasConcept C71315377 @default.
• W2030571880 hasConcept C71924100 @default.
• W2030571880 hasConcept C86803240 @default.
• W2030571880 hasConceptScore W2030571880C126322002 @default.
• W2030571880 hasConceptScore W2030571880C134018914 @default.
• W2030571880 hasConceptScore W2030571880C141359234 @default.
• W2030571880 hasConceptScore W2030571880C170493617 @default.
• W2030571880 hasConceptScore W2030571880C185592680 @default.
• W2030571880 hasConceptScore W2030571880C2777369949 @default.
• W2030571880 hasConceptScore W2030571880C2779357093 @default.
• W2030571880 hasConceptScore W2030571880C2780352252 @default.
• W2030571880 hasConceptScore W2030571880C3018685816 @default.
• W2030571880 hasConceptScore W2030571880C4733338 @default.
• W2030571880 hasConceptScore W2030571880C48289651 @default.
• W2030571880 hasConceptScore W2030571880C71315377 @default.
• W2030571880 hasConceptScore W2030571880C71924100 @default.
• W2030571880 hasConceptScore W2030571880C86803240 @default.
• W2030571880 hasIssue "7" @default.
• W2030571880 hasLocation W20305718801 @default.
• W2030571880 hasLocation W20305718802 @default.
• W2030571880 hasOpenAccess W2030571880 @default.
• W2030571880 hasPrimaryLocation W20305718801 @default.
• W2030571880 hasRelatedWork W1518235890 @default.
• W2030571880 hasRelatedWork W1823058265 @default.

• next