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• W2030651927 endingPage "83" @default.
• W2030651927 startingPage "73" @default.
• W2030651927 abstract "Carnitine is a nonessential amino acid that has a central role in lipid peroxidation and mitochondrial metabolism. Carnitine deficiency is rare in adult human subjects who have a normal diet and no underlying chronic diseases. Studies have shown that HIV-infected patients are at increased risk of carnitine deficiency due to decreased intake, increased metabolism, gastrointestinal problems, HIV infection itself, concomitant infections, underlying disease, concomitant drugs and antiretroviral therapy. Decreased serum and muscle carnitine content was reported following antiretroviral therapy in HIV-positive patients. The beneficial effects of carnitine on the human immune system, such as prevention of CD4 cell apoptosis, was reported in these patients. Additionally, polyneuropathy, myopathy, lactic acidosis, dyslipidemia and lipodystrophy are complications of antiretroviral therapy that have been proposed to potentially be related to carnitine deficiency and mitochondrial dysfunction. Carnitine may have a significant role in improving some aspects of mitochondrial toxicity induced by an antiretroviral regimen, such as lipodystrophy. Also, there are nearly sufficient data to support the beneficial effects of carnitine in improving the symptoms of lactic acidosis following antiretroviral therapy. According to available data, it is concluded that carnitine may have beneficial effects in the treatment of antiretroviral-induced neuropathy. Most of the evidence supports carnitine supplementation as a treatment strategy rather than prophylaxis for antiretroviralinduced complications. Several studies have shown the prevalence of carnitine deficiency and its role in different aspects of infection and antiretroviral-induced complications in HIV-positive patients, but the probable beneficial effects of carnitine supplementation are not clear in this population. In this review, we have collected and categorized available evidence regarding the potential benefits of carnitine supplementation in HIV-infected individuals." @default.
• W2030651927 created "2016-06-24" @default.
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• W2030651927 date "2012-01-01" @default.
• W2030651927 modified "2023-09-26" @default.
• W2030651927 title "Potential benefits of carnitine in HIV-positive patients" @default.
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• W2030651927 cites W1971054353 @default.
• W2030651927 cites W1971787612 @default.
• W2030651927 cites W1978803727 @default.
• W2030651927 cites W1978902758 @default.
• W2030651927 cites W1979665383 @default.
• W2030651927 cites W1979754581 @default.
• W2030651927 cites W1981203140 @default.
• W2030651927 cites W1985193136 @default.
• W2030651927 cites W1987396271 @default.
• W2030651927 cites W1993893510 @default.
• W2030651927 cites W1997634093 @default.
• W2030651927 cites W1998583291 @default.
• W2030651927 cites W1998596148 @default.
• W2030651927 cites W2001172623 @default.
• W2030651927 cites W2002148990 @default.
• W2030651927 cites W2008681391 @default.
• W2030651927 cites W2020147681 @default.
• W2030651927 cites W2020491388 @default.
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• W2030651927 cites W2022225339 @default.
• W2030651927 cites W2023469655 @default.
• W2030651927 cites W2023592074 @default.
• W2030651927 cites W2027285541 @default.
• W2030651927 cites W2034760164 @default.
• W2030651927 cites W2041773560 @default.
• W2030651927 cites W2041841997 @default.
• W2030651927 cites W2042999409 @default.
• W2030651927 cites W2043427266 @default.
• W2030651927 cites W2044839807 @default.
• W2030651927 cites W2048211624 @default.
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• W2030651927 cites W2060458404 @default.
• W2030651927 cites W2063244503 @default.
• W2030651927 cites W2063710614 @default.
• W2030651927 cites W2075030338 @default.
• W2030651927 cites W2075669690 @default.
• W2030651927 cites W2078273357 @default.
• W2030651927 cites W2078324852 @default.
• W2030651927 cites W2082088685 @default.
• W2030651927 cites W2083405476 @default.
• W2030651927 cites W2083600593 @default.
• W2030651927 cites W2083996184 @default.
• W2030651927 cites W2084890679 @default.
• W2030651927 cites W2092195709 @default.
• W2030651927 cites W2094294841 @default.
• W2030651927 cites W2101970528 @default.
• W2030651927 cites W2109532027 @default.
• W2030651927 cites W2111337675 @default.
• W2030651927 cites W2116315449 @default.
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• W2030651927 cites W2119665407 @default.
• W2030651927 cites W2142402689 @default.
• W2030651927 cites W2146401731 @default.
• W2030651927 cites W2149179835 @default.
• W2030651927 cites W2150141316 @default.
• W2030651927 cites W2150961630 @default.
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• W2030651927 cites W2169588149 @default.
• W2030651927 cites W2319296752 @default.
• W2030651927 cites W2329831060 @default.
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• W2030651927 doi "https://doi.org/10.2217/fvl.11.133" @default.
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