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• W2030699054 endingPage "1449" @default.
• W2030699054 startingPage "1438" @default.
• W2030699054 abstract "The events that convert adherent epithelial cells into individual migratory cells that can invade the extracellular matrix are known collectively as epithelial-mesenchymal transition (EMT). Throughout evolution, the capacity of cells to switch between these two cellular states has been fundamental in the generation of complex body patterns. Here, we review the EMT events that build the embryo and further discuss two prototypical processes governed by EMT in amniotes: gastrulation and neural crest formation. Cells undergo EMT to migrate and colonize distant territories. Not surprisingly, this is also the mechanism used by cancer cells to disperse throughout the body." @default.
• W2030699054 created "2016-06-24" @default.
• W2030699054 creator A5019521298 @default.
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• W2030699054 creator A5023445425 @default.
• W2030699054 creator A5067203728 @default.
• W2030699054 creator A5085342893 @default.
• W2030699054 date "2009-06-01" @default.
• W2030699054 modified "2023-10-15" @default.
• W2030699054 title "Epithelial-mesenchymal transitions: the importance of changing cell state in development and disease" @default.
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