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- W2030702979 abstract "Protein biosynthesis in bacteria is controlled by a number of translation factors. Recent data based on comparison of sequence and structure data of translation factors have established a novel hypothesis for their interaction with the ribosome: initiation, elongation, and termination factors may use a common or partly overlapping binding site on the ribosome in a process of macromolecular mimicry of an A-site-bound tRNA. This paper reviews structural knowledge and tRNA macromolecular mimicry involvement of translation initiation factor IF2. Furthermore, a model is proposed for the factor and its interaction with the ribosome during the formation of the translation initiation complex." @default.
- W2030702979 created "2016-06-24" @default.
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- W2030702979 date "2000-12-01" @default.
- W2030702979 modified "2023-10-17" @default.
- W2030702979 title "Macromolecular Mimicry in Translation Initiation: A Model for the Initiation Factor IF2 on the Ribosome" @default.
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- W2030702979 doi "https://doi.org/10.1080/713803743" @default.
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