Matches in SemOpenAlex for { <https://semopenalex.org/work/W2030713054> ?p ?o ?g. }
Showing items 1 to 66 of
66
with 100 items per page.
- W2030713054 endingPage "543" @default.
- W2030713054 startingPage "538" @default.
- W2030713054 abstract "The observation that revelation of immunocryptic epitopes in self-antigens may initiate the autoimmune response has prompted the search for processes that induce novel autoantigen structure as potential initiators of autoimmunity. Recent studies have demonstrated that the autoantigens targeted in diffuse scleroderma are unified by their enrichment in nucleolini and by their susceptibility to fragmentation in a novel metal-dependent reaction that requires the generation of reactive oxygen species. Several other studies highlight the importance of reactive oxygen species as mediators of damage during ischemia-reperfusion and present evidence for increased generation of these radicals in patients with scleroderma. Together, these studies suggest a model for the pathogenesis of scleroderma in which metals and free radicals play a central, autoamplifying role." @default.
- W2030713054 created "2016-06-24" @default.
- W2030713054 creator A5004540531 @default.
- W2030713054 creator A5008833389 @default.
- W2030713054 creator A5068528030 @default.
- W2030713054 date "1997-11-01" @default.
- W2030713054 modified "2023-10-11" @default.
- W2030713054 title "Role of metal-catalyzed oxidation reactions in the early pathogenesis of scleroderma" @default.
- W2030713054 doi "https://doi.org/10.1097/00002281-199711000-00010" @default.
- W2030713054 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/9375283" @default.
- W2030713054 hasPublicationYear "1997" @default.
- W2030713054 type Work @default.
- W2030713054 sameAs 2030713054 @default.
- W2030713054 citedByCount "41" @default.
- W2030713054 countsByYear W20307130542012 @default.
- W2030713054 countsByYear W20307130542014 @default.
- W2030713054 countsByYear W20307130542018 @default.
- W2030713054 countsByYear W20307130542022 @default.
- W2030713054 crossrefType "journal-article" @default.
- W2030713054 hasAuthorship W2030713054A5004540531 @default.
- W2030713054 hasAuthorship W2030713054A5008833389 @default.
- W2030713054 hasAuthorship W2030713054A5068528030 @default.
- W2030713054 hasConcept C139066938 @default.
- W2030713054 hasConcept C159654299 @default.
- W2030713054 hasConcept C180032290 @default.
- W2030713054 hasConcept C185592680 @default.
- W2030713054 hasConcept C203014093 @default.
- W2030713054 hasConcept C2779967694 @default.
- W2030713054 hasConcept C2780130043 @default.
- W2030713054 hasConcept C2780942790 @default.
- W2030713054 hasConcept C48349386 @default.
- W2030713054 hasConcept C55493867 @default.
- W2030713054 hasConcept C71924100 @default.
- W2030713054 hasConceptScore W2030713054C139066938 @default.
- W2030713054 hasConceptScore W2030713054C159654299 @default.
- W2030713054 hasConceptScore W2030713054C180032290 @default.
- W2030713054 hasConceptScore W2030713054C185592680 @default.
- W2030713054 hasConceptScore W2030713054C203014093 @default.
- W2030713054 hasConceptScore W2030713054C2779967694 @default.
- W2030713054 hasConceptScore W2030713054C2780130043 @default.
- W2030713054 hasConceptScore W2030713054C2780942790 @default.
- W2030713054 hasConceptScore W2030713054C48349386 @default.
- W2030713054 hasConceptScore W2030713054C55493867 @default.
- W2030713054 hasConceptScore W2030713054C71924100 @default.
- W2030713054 hasIssue "6" @default.
- W2030713054 hasLocation W20307130541 @default.
- W2030713054 hasLocation W20307130542 @default.
- W2030713054 hasOpenAccess W2030713054 @default.
- W2030713054 hasPrimaryLocation W20307130541 @default.
- W2030713054 hasRelatedWork W1496977441 @default.
- W2030713054 hasRelatedWork W2008448835 @default.
- W2030713054 hasRelatedWork W2015420494 @default.
- W2030713054 hasRelatedWork W2025743000 @default.
- W2030713054 hasRelatedWork W2215346036 @default.
- W2030713054 hasRelatedWork W2365906682 @default.
- W2030713054 hasRelatedWork W2370957413 @default.
- W2030713054 hasRelatedWork W2951724433 @default.
- W2030713054 hasRelatedWork W3215180497 @default.
- W2030713054 hasRelatedWork W4252501833 @default.
- W2030713054 hasVolume "9" @default.
- W2030713054 isParatext "false" @default.
- W2030713054 isRetracted "false" @default.
- W2030713054 magId "2030713054" @default.
- W2030713054 workType "article" @default.