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• W2030746089 abstract "Summary Vincristine was given to rats in which thrombocytopoiesis was either normal or acutely or chronically stimulated by injections of heterologous antiplatelet serum. A single dose of 0.3 mg/kg was given intravenously. The drug produced an early and a delayed megakaryocytopenia suggesting that it was toxic to differentiated megakaryocytes as well as to proliferating stem cells. The results support the hypothesis that vincristine-induced thrombocytosis may be due to homeostatic adjustments which, in turn, are activated as a result of drug-induced cytotoxicity." @default.
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• W2030746089 date "1975-04-01" @default.
• W2030746089 modified "2023-10-16" @default.
• W2030746089 title "Effects of Vincristine on Normal and Stimulated Megakaryocytopoiesis in the Rat" @default.
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• W2030746089 doi "https://doi.org/10.1111/j.1365-2141.1975.tb02746.x" @default.
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