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- W2030781146 abstract "We present Computed Tomography (CT) acquisition and reconstruction schemes for low-dose neuro-angiography basedon the method of HighlY constrained back PRojection (HYPR). Simulated and experimental low X-ray radiation dosescans were prepared using the techniques of interleaved view angle under-sampling and tube current reduction.Dynamic CT Angiograms (CTAs) were produced for both standard and low dose images sets. The spatial correlationcoefficient, r, between the two reconstruction approaches was determined for each time frame and the SNR and CNRvalues in arterial ROIs were calculated. The undersampled HYPR reconstructions produced r values of > 0.95 at undersamplingand dose reduction factors of 10 and SNR and CNR were more than doubled using HYPR techniques at a tubecurrent of 25 mA. HYPR approaches to contrast enhanced neuro-imaging provide not only volumetric brainhemodynamics but also the ability to produce high quality maps of standard perfusion parameters. The synergy ofvolumetric hemodynamics and assessment of tissue function provides the medical imaging community with high qualitydiagnostic information at a fraction of the radiation dose in a single contrast-enhanced scan." @default.
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- W2030781146 date "2008-03-06" @default.
- W2030781146 modified "2023-09-26" @default.
- W2030781146 title "An acquisition and image reconstruction scheme for reduced x-ray exposure dynamic 3D CTA" @default.
- W2030781146 doi "https://doi.org/10.1117/12.772656" @default.
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