Matches in SemOpenAlex for { <https://semopenalex.org/work/W2030789968> ?p ?o ?g. }
Showing items 1 to 80 of
80
with 100 items per page.
- W2030789968 endingPage "580" @default.
- W2030789968 startingPage "580" @default.
- W2030789968 abstract "Syrian hamsters are exquisitely sensitive to clindamycin; as little as 1 mg/kg of clindamycin given systemically causes a fatal colitis. Clindamycin and erythromycin were applied topically daily to the shaved backs of Syrian hamsters in a hydroalcoholic vehicle. A daily dose of 0.1 mg of clindamycin was lethal to more than half the hamsters and 1 mg to all the animals. The antibiotic-associated toxin from Clostridium difficile was present in their cecal material. Based on body surface areas and estimated usual volumes applied, the lethal dose in hamsters is not dissimilar to that given humans for acne. Oral tetracycline therapy protected the animals from clindamycin toxicity, but the animals died three days after stopping tetracycline if topical clindamycin applications were continued." @default.
- W2030789968 created "2016-06-24" @default.
- W2030789968 creator A5028687168 @default.
- W2030789968 creator A5040003817 @default.
- W2030789968 creator A5054816883 @default.
- W2030789968 creator A5090346378 @default.
- W2030789968 date "1979-05-01" @default.
- W2030789968 modified "2023-10-07" @default.
- W2030789968 title "Induction of Colitis in Hamsters by Topical Application of Antibiotics" @default.
- W2030789968 cites W1233276 @default.
- W2030789968 cites W159390050 @default.
- W2030789968 cites W2011755795 @default.
- W2030789968 cites W2017089452 @default.
- W2030789968 cites W2045373518 @default.
- W2030789968 cites W2049572154 @default.
- W2030789968 cites W2057602015 @default.
- W2030789968 cites W2061041840 @default.
- W2030789968 cites W2067856230 @default.
- W2030789968 cites W2129119364 @default.
- W2030789968 cites W2324303752 @default.
- W2030789968 cites W2331725203 @default.
- W2030789968 cites W2415556138 @default.
- W2030789968 cites W2473713030 @default.
- W2030789968 doi "https://doi.org/10.1001/archderm.1979.04010050014005" @default.
- W2030789968 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/571698" @default.
- W2030789968 hasPublicationYear "1979" @default.
- W2030789968 type Work @default.
- W2030789968 sameAs 2030789968 @default.
- W2030789968 citedByCount "18" @default.
- W2030789968 countsByYear W20307899682012 @default.
- W2030789968 countsByYear W20307899682013 @default.
- W2030789968 crossrefType "journal-article" @default.
- W2030789968 hasAuthorship W2030789968A5028687168 @default.
- W2030789968 hasAuthorship W2030789968A5040003817 @default.
- W2030789968 hasAuthorship W2030789968A5054816883 @default.
- W2030789968 hasAuthorship W2030789968A5090346378 @default.
- W2030789968 hasConcept C126322002 @default.
- W2030789968 hasConcept C2777458120 @default.
- W2030789968 hasConcept C2778575167 @default.
- W2030789968 hasConcept C2779525107 @default.
- W2030789968 hasConcept C2780206985 @default.
- W2030789968 hasConcept C2780923616 @default.
- W2030789968 hasConcept C501593827 @default.
- W2030789968 hasConcept C71924100 @default.
- W2030789968 hasConcept C86803240 @default.
- W2030789968 hasConcept C89423630 @default.
- W2030789968 hasConcept C98274493 @default.
- W2030789968 hasConceptScore W2030789968C126322002 @default.
- W2030789968 hasConceptScore W2030789968C2777458120 @default.
- W2030789968 hasConceptScore W2030789968C2778575167 @default.
- W2030789968 hasConceptScore W2030789968C2779525107 @default.
- W2030789968 hasConceptScore W2030789968C2780206985 @default.
- W2030789968 hasConceptScore W2030789968C2780923616 @default.
- W2030789968 hasConceptScore W2030789968C501593827 @default.
- W2030789968 hasConceptScore W2030789968C71924100 @default.
- W2030789968 hasConceptScore W2030789968C86803240 @default.
- W2030789968 hasConceptScore W2030789968C89423630 @default.
- W2030789968 hasConceptScore W2030789968C98274493 @default.
- W2030789968 hasIssue "5" @default.
- W2030789968 hasLocation W20307899681 @default.
- W2030789968 hasLocation W20307899682 @default.
- W2030789968 hasOpenAccess W2030789968 @default.
- W2030789968 hasPrimaryLocation W20307899681 @default.
- W2030789968 hasRelatedWork W1495827436 @default.
- W2030789968 hasRelatedWork W2099772106 @default.
- W2030789968 hasRelatedWork W2111015760 @default.
- W2030789968 hasRelatedWork W2348466235 @default.
- W2030789968 hasRelatedWork W2359572154 @default.
- W2030789968 hasRelatedWork W2361731146 @default.
- W2030789968 hasRelatedWork W2362960946 @default.
- W2030789968 hasRelatedWork W2377402670 @default.
- W2030789968 hasRelatedWork W2390382535 @default.
- W2030789968 hasRelatedWork W2391187375 @default.
- W2030789968 hasVolume "115" @default.
- W2030789968 isParatext "false" @default.
- W2030789968 isRetracted "false" @default.
- W2030789968 magId "2030789968" @default.
- W2030789968 workType "article" @default.