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W2030822503 abstract "Multiple endocrine neoplasia type 1 (MEN 1) is an autosomal dominant disorder characterized by the development of parathyroid hyperplasia, pancreatic endocrine tumors, pituitary adenomas, and adrenal adenomas. We reported 1 case of MEN 1 simultaneous with gastrinoma and insulinoma; meanwhile, insulinomas were ectopic and recurrent. The genetic screening showed the mutation of 427del AT of the MEN 1 gene. Surgical removal is considered the treatment of choice, with limited adverse effects and relatively low morbidity and mortality. She was treated by means of several surgical strategies, resulting in improvement of the frequency and severity of the hypoglycemic episodes and a better quality of life. Abbreviation: MEN 1 - Multiple endocrine neoplasia type 1 syndrome, ZES - Zollinger-Ellison syndrome, NSE - neuron-specific enolase, SYN - synaptophysin" @default.
W2030822503 created "2016-06-24" @default.
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W2030822503 date "2010-07-01" @default.
W2030822503 modified "2023-10-15" @default.
W2030822503 title "Multiple Endocrine Neoplasia Type 1 Simultaneous With Various Types of Enteropancreatic Endocrine Tumors" @default.
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W2030822503 doi "https://doi.org/10.1097/mpa.0b013e3181d36341" @default.
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