FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2030828419> ?p ?o ?g. }

• W2030828419 endingPage "1019.e4" @default.
• W2030828419 startingPage "1010" @default.
• W2030828419 abstract "Objective There is consistent evidence that attention-deficit/hyperactivity disorder (ADHD) is strongly related to impaired motor timing as reflected in decreased accuracy and increased reaction time variability (RTV). It is not known whether motor timing impairments are present in adolescents and adults with ADHD and their unaffected relatives to the same extent as has been reported in children, and whether ADHD and motor timing share familial underpinnings, as reflected in parent–offspring co-segregation and sibling cross-correlations. Method A total of 589 parents and 808 children/adolescents from families with ADHD and control families (parent/offspring average age: 48.6/17.3 years) were included. All participants were thoroughly assessed for ADHD and performed a 40-trial motor timing task (1-second interval production). Dependent neurocognitive measures included RT median (RTM: representing accuracy), RTV and ex-Gaussian component τ (τ: representing infrequent long response times). Generalized estimating equations were used for analyses. Results Unaffected children from families with ADHD had RTV (but not RTM or τ) scores in between those of affected and control children. However, during middle-to-late adolescence, unaffected offspring were not impaired compared to control offspring and differed from ADHD probands, whereas during late adolescence/early adulthood, all offspring groups performed equally. Affected and unaffected parents of families with ADHD showed increased RTV compared to controls, regardless of age (not significant after adjusting for IQ). There were indications for shared familiality between RTV and ADHD as reflected by sibling cross-correlations and between RTM and ADHD as reflected by sibling cross-correlations and a maternal parent–offspring relation (parent-of-origin effect). Conclusions RTV and its familial characteristics are influenced by development during adolescence. Increased RTV in children with ADHD appears to reflect immaturities in their neurocognitive functioning. Maternal ADHD effects might be involved in transmission of RTM (not RTV), but overall RTM showed less compelling (familial) relationships with ADHD than RTV. There is consistent evidence that attention-deficit/hyperactivity disorder (ADHD) is strongly related to impaired motor timing as reflected in decreased accuracy and increased reaction time variability (RTV). It is not known whether motor timing impairments are present in adolescents and adults with ADHD and their unaffected relatives to the same extent as has been reported in children, and whether ADHD and motor timing share familial underpinnings, as reflected in parent–offspring co-segregation and sibling cross-correlations. A total of 589 parents and 808 children/adolescents from families with ADHD and control families (parent/offspring average age: 48.6/17.3 years) were included. All participants were thoroughly assessed for ADHD and performed a 40-trial motor timing task (1-second interval production). Dependent neurocognitive measures included RT median (RTM: representing accuracy), RTV and ex-Gaussian component τ (τ: representing infrequent long response times). Generalized estimating equations were used for analyses. Unaffected children from families with ADHD had RTV (but not RTM or τ) scores in between those of affected and control children. However, during middle-to-late adolescence, unaffected offspring were not impaired compared to control offspring and differed from ADHD probands, whereas during late adolescence/early adulthood, all offspring groups performed equally. Affected and unaffected parents of families with ADHD showed increased RTV compared to controls, regardless of age (not significant after adjusting for IQ). There were indications for shared familiality between RTV and ADHD as reflected by sibling cross-correlations and between RTM and ADHD as reflected by sibling cross-correlations and a maternal parent–offspring relation (parent-of-origin effect). RTV and its familial characteristics are influenced by development during adolescence. Increased RTV in children with ADHD appears to reflect immaturities in their neurocognitive functioning. Maternal ADHD effects might be involved in transmission of RTM (not RTV), but overall RTM showed less compelling (familial) relationships with ADHD than RTV." @default.
• W2030828419 created "2016-06-24" @default.
• W2030828419 creator A5009149756 @default.
• W2030828419 creator A5010364628 @default.
• W2030828419 creator A5011987738 @default.
• W2030828419 creator A5017211020 @default.
• W2030828419 creator A5038874292 @default.
• W2030828419 creator A5039838663 @default.
• W2030828419 creator A5045226927 @default.
• W2030828419 creator A5060058426 @default.
• W2030828419 creator A5072775553 @default.
• W2030828419 date "2014-09-01" @default.
• W2030828419 modified "2023-09-26" @default.
• W2030828419 title "Attention-Deficit/Hyperactivity Disorder (ADHD) and Motor Timing in Adolescents and Their Parents: Familial Characteristics of Reaction Time Variability Vary With Age" @default.
• W2030828419 cites W1964284903 @default.
• W2030828419 cites W1974427281 @default.
• W2030828419 cites W1976131886 @default.
• W2030828419 cites W1983302342 @default.
• W2030828419 cites W2004420885 @default.
• W2030828419 cites W2005009229 @default.
• W2030828419 cites W2012675790 @default.
• W2030828419 cites W2012696549 @default.
• W2030828419 cites W2017588448 @default.
• W2030828419 cites W2021519456 @default.
• W2030828419 cites W2021849865 @default.
• W2030828419 cites W2027464692 @default.
• W2030828419 cites W2028198585 @default.
• W2030828419 cites W2030870175 @default.
• W2030828419 cites W2037689983 @default.
• W2030828419 cites W2040092455 @default.
• W2030828419 cites W2042961699 @default.
• W2030828419 cites W2072495786 @default.
• W2030828419 cites W2091199323 @default.
• W2030828419 cites W2095424470 @default.
• W2030828419 cites W2098033776 @default.
• W2030828419 cites W2098534178 @default.
• W2030828419 cites W2100666612 @default.
• W2030828419 cites W2103400599 @default.
• W2030828419 cites W2109413825 @default.
• W2030828419 cites W2115861555 @default.
• W2030828419 cites W2118635417 @default.
• W2030828419 cites W2119868885 @default.
• W2030828419 cites W2120600980 @default.
• W2030828419 cites W2123520594 @default.
• W2030828419 cites W2130195204 @default.
• W2030828419 cites W2131171370 @default.
• W2030828419 cites W2131809874 @default.
• W2030828419 cites W2134672718 @default.
• W2030828419 cites W2134971067 @default.
• W2030828419 cites W2136109876 @default.
• W2030828419 cites W2141032973 @default.
• W2030828419 cites W2143079975 @default.
• W2030828419 cites W2144579914 @default.
• W2030828419 cites W2146293650 @default.
• W2030828419 cites W2146738944 @default.
• W2030828419 cites W2146803093 @default.
• W2030828419 cites W2147957248 @default.
• W2030828419 cites W2148410950 @default.
• W2030828419 cites W2148776631 @default.
• W2030828419 cites W2148800933 @default.
• W2030828419 cites W2149467627 @default.
• W2030828419 cites W2150432411 @default.
• W2030828419 cites W2151770129 @default.
• W2030828419 cites W2153380054 @default.
• W2030828419 cites W2156645869 @default.
• W2030828419 cites W2162256563 @default.
• W2030828419 cites W2170334322 @default.
• W2030828419 cites W4236481034 @default.
• W2030828419 cites W4241039556 @default.
• W2030828419 cites W4247665917 @default.
• W2030828419 doi "https://doi.org/10.1016/j.jaac.2014.05.015" @default.
• W2030828419 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/25151424" @default.
• W2030828419 hasPublicationYear "2014" @default.
• W2030828419 type Work @default.
• W2030828419 sameAs 2030828419 @default.
• W2030828419 citedByCount "19" @default.
• W2030828419 countsByYear W20308284192014 @default.
• W2030828419 countsByYear W20308284192015 @default.
• W2030828419 countsByYear W20308284192016 @default.
• W2030828419 countsByYear W20308284192017 @default.
• W2030828419 countsByYear W20308284192018 @default.
• W2030828419 countsByYear W20308284192019 @default.
• W2030828419 countsByYear W20308284192021 @default.
• W2030828419 countsByYear W20308284192022 @default.
• W2030828419 countsByYear W20308284192023 @default.
• W2030828419 crossrefType "journal-article" @default.
• W2030828419 hasAuthorship W2030828419A5009149756 @default.
• W2030828419 hasAuthorship W2030828419A5010364628 @default.
• W2030828419 hasAuthorship W2030828419A5011987738 @default.
• W2030828419 hasAuthorship W2030828419A5017211020 @default.
• W2030828419 hasAuthorship W2030828419A5038874292 @default.
• W2030828419 hasAuthorship W2030828419A5039838663 @default.
• W2030828419 hasAuthorship W2030828419A5045226927 @default.
• W2030828419 hasAuthorship W2030828419A5060058426 @default.
• W2030828419 hasAuthorship W2030828419A5072775553 @default.
• W2030828419 hasConcept C104317684 @default.
• W2030828419 hasConcept C112672928 @default.
• W2030828419 hasConcept C118552586 @default.

• next